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Journal and News Scan

Source: Interdisciplinary Cardiovascular and Thoracic Surgery
Author(s): Katja Schumacher, Mateo Marin Cuartas, Manuela de la Cuesta, Thilo Noack, Philipp Kiefer, Sergey Leontyev, Michael A Borger, Marcel Vollroth, Martin Misfeld

The use of minimally invasive mitral valve surgery (MIMVS) has increased in recent years, and surgeons are seeing more patients requiring reoperation after MIMVS. This study analyzed early outcomes and long-term survival in this group. A total of 187 patients were included, with 18 percent undergoing repeat mitral valve (MV) repair and 82 percent undergoing MV replacement. Redo mitral valve surgery (MVS) was completed via median sternotomy in 90 percent of cases. Thirty-day mortality was 6.4 percent. Estimated five and twelve year survival were 62 percent and 38 percent, respectively. Preoperative stroke and infective endocarditis were independent predictors of long-term mortality. The research found that redo MVS can be performed safely in this group, yielding low early mortality and acceptable long-term survival rates.

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Lars G. Svensson

In his presidential address to the AATS annual congregation, Dr. Lars Svensson shared ideas and insights into CT surgeons’ purpose as physicians, what it takes to become a master surgeon (40,000 hours), how surgery is similar to car racing, and what it takes to push the limits of what is possible to drive progress and innovation. He discusses the values of vision and leadership, shares a mantra for success and attaining the highest quality patient care possible, and discusses ways to reach such a lofty goal. He also touches on the importance of building a great team, and how to lead such a team, devise a strategy, and measure progress along the way. This is a thorough, elaborate, and eloquent address that is thought provoking and inspirational.

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Jean-Luc A. Maigrot, Aaron J. Weiss, Andrea M. Steely, Austin Firth, David Moros, Eugene H. Blackstone, Nicholas G. Smedira

This article summarizes the outcomes of 940 patients who underwent transaortic septal myectomy at Cleveland Clinic over a period of five years. A total of 682 (73 percent) of these patients had midventricular and/or apical resection, of which 582 (85 percent) had basal plus midventricular resection and 78 (11 percent) had basal, midventricular, and apical resection. The median resection weight was 10 grams. The authors describe the safety and feasibility of this transaortic approach to midventricular and apical septal myomectomy in experienced hands and report that no patients underwent a left ventriculotomy for the procedure. They also detail how extending beyond the basal septum is important to prevent residual obstruction.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Satoshi Asada, Shinichiro Oda, Yoshinobu Maeda, Shuhei Fujita, Hisayuki Hongu, Eijiro Yamashita, Hiroki Nakatsuji, Takashi Nagase, Rie Nakai, Takaaki Hayashi, Jin Ikarashi, Yasutaka Goto, Masaaki Yamagishi

For hypoplastic left heart syndrome patients undergoing staged reconstruction, the neoaortic root can dilate so that the incidence of neoaortic valve insufficiency increases over time. This article aims to evaluate the outcomes of neoaortic root geometries and valvular function after chimney reconstruction in the Norwood operation in 20 patients. Researchers found that chimney reconstruction did allow patients to avoid significant neoaortic valve regurgitation and preserve conical configuration in the mid-term. However, further studies are needed to evaluate long term outcomes of this form of reconstruction.

Source: The Annals of Thoracic Surgery
Author(s): J. Hunter Mehaffey, J.W. Awori Hayanga, Lawrence M. Wei, Dhaval Chauhan, Christopher E. Mascio, J. Scott Rankin, Vinay Badhwar

In a national analysis of 19,524 patients with preoperative atrial fibrillation undergoing isolated coronary bypass grafting surgery (11,508 patients [58.9 percent]), left atrial appendage closure (4541 patients [23.3 percent]), or with concomitant ablation and left atrial appendage closure (3475 patients [17.8 percent]), concomitant left atrial appendage closure and ablation was associated with reduced stroke risk at three years (hazard ratio [HR], 0.74; P= .049) and improved survival (HR, 0.86; P= .016) compared with no concomitant atrial fibrillation procedure, and reduced stroke compared with left atrial appendage closure without ablation (HR, 0.75; P = .031).

Source: Journal of the American Heart Association
Author(s): Tulio Caldonazo, Stefan Hagel, Torsten Doenst, Hristo Kirov, Michel Pompeu Sá, Xander Jacquemyn, Panagiotis Tasoudis, Marcus Franz and Mahmoud Diab

Some patients with infective endocarditis receive exclusively conservative antibiotic treatment due to their comorbidities and high operative risk, despite fulfilling criteria for surgical therapy. Hence, this study aimed to compare the outcomes in patients with infective endocarditis and a surgical indication in those who underwent or did not undergo valve surgery. To this end, the authors performed a pooled analysis of Kaplan-Meier derived reconstructed time‐to‐event data from studies comparing conservative and surgical treatment. Four studies with a total of 3,003 patients and a median follow up time of 7.6 months were included. Overall, patients with an indication for surgery who were surgically treated had a significantly lower risk of mortality compared with patients who received conservative treatment (hazard ratio [HR], 0.27 [95 percent CI, 0.24–0.31], P <0.001). Survival was superior among patients who underwent surgery when compared with those who did not, at one month (87.6 percent versus 57.6 percent; HR, 0.31 [95 percent CI, 0.26–0.37], P <0.01), at 6 months (74.7 percent versus 34.6 percent), and at 12 months (73.3 percent versus 32.7 percent).

Source: The Annals of Thoracic Surgery
Author(s): Andrea L. Axtell, Henning A. Gaissert, Xiaodong Bao, Hugh G. Auchincloss, Elisa Walsh, David C. Chang, Yolanda L. Colson, Michael Lanuti

Of 57,531 patients who underwent lung cancer resection identified from The Society of Thoracic Surgeons General Thoracic Surgery Database, 758 (1.3 percent) were diagnosed with pulmonary embolism, which was most likely in patients with locally advanced disease who underwent bilobectomy (6 percent versus 4 percent, P < .001) or pneumonectomy (8 percent versus 5 percent, P < .001). Patients with postoperative pulmonary embolism had increased thirty-day mortality (14 percent versus 3 percent, P < .001), reintubation (25 percent versus 8 percent, P < .001), and readmission (49 percent versus 15 percent, P < .001). Black race (odds ratio, 1.74; 95 percent CI, 1.39-2.16; P < .001), interstitial fibrosis (odds ratio, 1.77; 95 percent CI, 1.15-2.72; P = .009), extent of resection, and increased operative duration were independently predictive, and a minimally invasive approach compared with thoracotomy was protective.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Hristian Hinkov, Chong Bin Lee, Leonard Pitts, Pia Lanmüller, Christoph Klein, Marian Kukucka, Evgenij Potapov, Jörg Kempfert, Volkmar Falk, Henryk Dreger, Axel Unbehaun

Aortic valve regurgitation (AR) often occurs after left ventricular assist device (LVAD) implantation. Transcatheter aortic valve implantation (TAVI) is a viable alternative to surgical aortic valve replacement (SAVR) in this cohort, most of whom have a high surgical risk profile. Procedure outcome and survival were analyzed. From 2017 to 2023, 27 LVAD patients with significant AR received elective or urgent TAVI at this center. Of these patients, 25 percent had device landing zone pre-stenting followed by a standard TAVI device and 59 percent received standard TAVI devices, with 37 percent of these patients requiring a second transcatheter heart valve (THV). Aortic regurgitation in more than trace amounts affected 6 percent of patients at discharge. Fifteen percent received AR-dedicated TAVI devices, with none requiring a second THV and no AR at discharge. TAVI has promising outcomes and survival in LVAD patients, with tailored devices and pre-stenting enhancing procedure success.

Source: ABC News
Author(s): Mary Kekatos

A fifty-four-year-old woman became the first person to simultaneously receive a gene-edited pig kidney transplant and mechanical heart valve implantation. Surgeons performed the heart pump procedure first before performing the transplant days later. Due to the severity of her condition, the patient was not eligible for traditional kidney transplant, but is doing well after the innovative procedure was performed on April 11.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Bahaaldin Alsoufi, Deborah Kozik, Melissa Perrotta, Sarah Wilkens, Andrea Nicole Lambert, Shriprasad Deshpande, Mark Slaughter, Jaimin Trivedi

Heart transplantation for adult congenital heart disease (ACHD) is associated with challenging pretransplant support, long waitlists, and high early post-transplant mortality. The authors used 2,737 patients from the United Network for Organ Sharing database to examine whether changing practices have altered outcomes in the period from 1992 to after 2018, when the allocation system changed. The listed and transplanted patients gradually increased, but the proportion receiving a transplant remained constant. There were decreases in both the proportion delisted or dying after listing and the waitlist times, especially after 2018. Mortality at 30 days post-transplant remains high but has significantly improved. The authors concluded that more complex patients do not have worse outcomes and that the new donor allocation system has reduced wait times without affecting early mortality.

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