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LUNG CANCER
A Handbook for Staging, Imaging, and Lymph Node Classification
by Clifton F. Mountain, MD; Herman I. Libshitz, MD; and Kay E. Hermes
Contents | About the Author(s) | Dedication and Acknowledgment
 The Revised Staging System for Lung Cancer
page 6 

TNM DEFINITIONS (continued)
N - Nodal Involvement

N0
No demonstrable metastasis to regional lymph nodes.
N1
Metastasis to lymph nodes in the peribronchial or the ipsilateral hilar region, or both, including direct extension.
N2
Metastasis to ipsilateral mediastinal lymph nodes and subcarinal lymph nodes.
N3
Metastasis to contralateral mediastinal lymph nodes, contralateral hilar lymph nodes, ipsilateral or contralateral scalene or supraclavicular lymph nodes.

M - Distant Metastasis

M0
No (known) distant metastasis
M1
Distant metastasis present***. Specify site(s)

Footnotes:

*T1: The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall which may extend proximal to the main bronchus is classified as T1.

**T4: Most pleural effusions associated with lung cancer are due to tumor. There are, however, some few patients in whom cytopathological examination of pleural fluid (on more than one specimen) is negative for tumor, the fluid is non-bloody and is not an exudate. In such cases where these elements and clinical judgment dictate that the effusion is not related to the tumor, the patients should be staged T1, T2 or T3, excluding effusion as a staging element.

***M1: Separate metastatic tumor nodules in the ipsilateral nonprimary tumor lobe(s) of the lung also are classified M1.

Copyright © 1999 - 2003 by CF Mountain and HI Libshitz, Houston, Texas. All rights reserved.

Printed in the United States of America by Charles P. Young Company. No part of this manual may be reproduced by any means without the prior written consent of the authors.