Thoracoscopic staging for esophageal cancer

Originating Group

CALGB 9380

P.I.: Dr. M. Krasna

Participating Groups

Objectives

1. To evaluate the feasibility, morbidity and mortality of preoperative staging thoracoscopy/laparoscopy for esophageal cancer
2. To assess the accuracy of lymph node staging by thoracoscopy/laparoscopy through comparison to final pathologic staging
3. To assess the benefit of thoracoscopy/laparoscopy when added to clinical staging
4. To assess the costs of throacoscopic/laparoscopic lymph node (TSLN/LSLN) staging and the possible savings of avoiding unnecessary esophagectomy

Eligibility

1. Histologically codumented squamous cell carcinoma or adenocarcinoma of the thoracic (below 20 cm) esophagusor geastroesophageal junction is required
2. No distant metastases or local invasion of adjacent structures
3. Suitable for thoracoscopy and laparoscopy
4. Age >= 18 years
5. Informed consent and IRB approval within one year
6. No prior chemotherapy or readiotherapy within past five years
7. Performance status 0-2
8. Evaluation by thoracic surgeon

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