Myocardial Protection and Cardiopulmonary Bypass Selected References

Selected Articles

Brown WM 3rd, Horsley WS, Gott JP, Bufkin BL, Guyton RA. Myocardial protection for coronary artery bypass in patients with acute myocardial infarction. Seminars in Thoracic and Cardiovascular Surgery 1995 7 (4):191-7.
This article covers the particular challenge of protecting the heart compromised from infarction. The Buckberg and Emory reperfusion protocols are outlined and their merits discussed.

Cordell AR. Milestones in the development of cardioplegia. Annals of Thoracic Surgery 1995 60(3):793-6.

A historical article with highlights major contributions in cardioplegia. A second article in the same issue specifically covers warm cardioplegia.

Hammermeister KE, Burchfiel C, Johnson R, Grover FL. Identification of patients at greatest risk for developing major complications at cardiac surgery. Circulation 1990 82(5 Suppl):IV380-9.

Analysis of over 10,000 patients shows that previous cardiac surgery is a strong predictor for the development of postop complications, and patients who develop complications have a 8-10 fold increase in operative mortality.

Ohri SK, Desai JB, Gaer JA, Roussak JB, Hashemi M, Smith Pl, Taylor KM. Intraabdominal complications after cardiopulmonary bypass. Annals of Thoracic Surgery 1991 52(4):826-31.

Although such events are uncommon, this series demonstrates a correlation between prolonged CPB time and development of abdominal complications. As expected, mortality is higher than in those patients without such problems.

Arom KV, Emery RW, Petersen RJ, Bero JW. Evaluation of 7,000+ patients with two different routes of cardioplegia. Annals of Thoracic Surgery 1997 63(6):1619-24.

This retrospective review compares retrograde cardioplegia to combined antegrade/retrograde cardioplegia. The techniques were essentially equivalent for myocardial protection.

Sources for further reading

Textbook Chapters
Chapters 2 and 3: Hypothermia, Circulatory Arrest, and Cardiopulmonary Bypass; Myocardial Management During Cardiac Surgery with Cardiopulmonary Bypass. Cardiac Surgery (Kirklin and Barratt-Boyes), 2nd ed., 61-165.

Glenn's Thoracic and Cardiovascular Surgery (Baue, Geha, Hammond, Laks, and Naunheim), 6th ed., , 1599-1616.


Recent on-line full-text journal articles

Annals of Thoracic Surgery

Journal of Thoracic and Cardiovascular Surgery