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ABSTRACT 19
IS THE GRAFTCONNECTOR A VALID ALTERNATIVE TO
RUNNING SUTURE IN END-TO-SIDE CORONARY ARTERIES ANASTOMOSES?
P. Tozzi, J.O. Solem*, D. Boumzebra*, C.Y.Genton**, P.Chaubert**,
A. Mucciolo, L.K.von Segesser
Cardiovascular Surgery Dpt, **Pathology DPT University of Lausanne,
Switzerland
*King Faisal Hospital, Riyadh, Saudi Arabia
INTRODUCTION: An animal study was done to compare long
term patency rate and anastomotic diameter of coronary anastomoses
performed with Graftconnector Vs running suture technique.
METHODS: 10 sheep, 45-55 kg, underwent OPCABG (RIMA on
LAD). In 5 animals, the anastomosis was performed with Graftconnector
and in 5 animals with 7-0 running suture. Intraoperatory fluoroscopy
and 6 months control were performed. Animals received Ticlopidine
250mg/day for 4 weeks and Aspirin 100mg/day for 6 months, then
were sacrificed and histological examination of anastomoses were
done.
RESULTS
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ANASTOMOSIS
|
GRAFTCONNECTOR |
CONTROL
|
|
Patency
|
5/5 100%
|
5/5 100%
|
|
Ø at 6 months fluoroscopy
|
118%*
|
97%*
|
|
Luminal width at histology
|
1,7 ±0,2mm
|
1,6±0,1mm
|
|
Cross-sectional area
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64.4%**
|
95%*
|
|
Intimal hyperplasia thickness
|
0.21±0.1 mm
|
0.01mm
|
|
Inflammatory reaction
|
Giant cells
|
None
|
*Percentage of native LAD; **percentage of overexpanded LAD
CONCLUSIONS
Myointimal hyperplasia was more important in Graftconnector
group probably because of devices oversizing at the implantation.
Long-term results demonstrate that OPCABG performed with Graftconnector
had the same patency rate and luminal width as those performed
with running suture.
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