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John Markley

John G. Markley, M.D.

Harry S Truman Memorial Veterans Hospital
800 Hospital Drive, CT Specialty Care
Columbia, MO  65201
United States
1 573 814-6562/5
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Role: 
Surgeon - Cardiothoracic

Background

Oncology Research, VA Hosp Sepulveda, CA, 1986-1988
Staff Research Associate, UCLA Oncology 1987-1988
Cardiothoracic Research: Left Ventricular Assist, Myocardial Stunning (Medical College of Wisconsin 1995-1997)
Military: Entered Active Duty Army July 2002, ETS July 2012
MIlitary: OBC July-Sept 2002
1) Military deployment: 31st Combat Support Hospital, Baghdad, Iraq (Jan04-Aug04)
2) Military deployment: 47th Combat Support Hospital, Mosul, Iraq (Aug09-Feb10)
3) Missouri Heart Center, Boone Hospital Center, Columbia, MO: April 2011 through June 2013; June 2015 through present
4) University of Missouri Hospitals and Clinics, Columbia, MO: September 2003 through Jan 2012 (Asst Clin Prof, CDivision Chief 2007-2009) ; June 2014 through August 2018 (Adj Asst Clin Prof)
5) Truman VA Hospital, Columbia, MO: Oct 2002 through present; Chief, Cardiothoracic Surgery September 2013 through present

Other Interests

TAVR and percutaneous valve therapies
Minimally invasive valve reconstruction
Thoracic Vascular and Complex Aortic/Arch Surgery
Adult acquired and adult congenital heart surgery
Performance and Quality Improvement
Military Support of Veterans Hospitals
Thoracic Surgery in the Modern Theater of Battle
Domestic Health Care Policy
Civil Disaster Preparedness (including resource utilization and allocation)
High End Audio, Music and Home Theater
Precision rifle shooting
Spending time with my family

Research

Research Experience

 

<              Clinical Research Fellowship: Affects of left heart assist on the right ventricle, septum and left ventricular stunning, Department of Cardiothoracic Surgery, Medical College of Wisconsin, July, 1995 through May, 1997.

<              Extracurricular Research project using western blotting to identify protease activity from metastatic clones of thyroid cancer, Department of Surgery, Medical College of Wisconsin, October 1991 to December, 1992.

<              Senior Elective, Research investigating carbocyanine laser dyes for argon laser photodynamic therapy of human tumor cells in vitro, Department of Surgical Oncology, University of California, Los Angeles, September 1991.

<              Staff Research Associate I, Research elucidating the mechanism of Rhodamine‑123 photo-chemo sensitization of human tumors in vitro using Argon Laser photodynamic therapy , Department of Head and Neck Surgery, University of California, Los Angeles, 1987‑88.

<              Laboratory Technician, Research project involving purification and characterization of urinary antigens to sarcomas, UCLA Department of Surgery, VA Medical Center, Sepulveda, California, 1986‑88.

 

Publications

 

  1. Castro DJ, Saxton RE, Markley JG, et al.: Argon Laser Phototherapy of Human Malignancies Using Rhodamine‑123 as a New Laser Dye: The Intracellular Role of Oxygen. Laryngoscope 1990; 100:884‑891.
  1. Markley JG and Nicolosi AC.: Effects of Left Heart Assist on Geometry and Function of the Interventricular Septum. Ann Thorac Surg 1996; 62:1752-8.
  1. Nicolosi AC, Markley JG, Olinger GN. Effects of postischemic left ventricular pressure-volume unloading on contractile recovery and myocardial blood flow in the regionally stunned canine heart. J Thorac Cardiovasc Surg 1999; 118(1):181-8.
  1. Nicolosi AC, West G, Markley JG, Logan B, Olinger GN: Gadolinium attenuates regional stunning in the canine heart in vivo. J Thorac Cardiovasc Surg 2002; 124: 57-62.
  1. Gopaldas RR, Tharakan AJ, Dao TK, Markley JG, Schmaltz RA. Glycoprotein IIB/IIIa Inhibitor Infusion Lowers Post-operative Bleeding And Mortality In Patients Undergoing Coronary Artery Bypass Grafting. J Surg Res. 2011 Jan; 165(2): 172-172.
  1. Gopaldas RR, Dao TK, Markley JG. The impact of surgeon specialty case-mix, volume and surgical technique on failure to rescue, morbidity and mortality following esophageal resections: A 11-year population based study. J Amer Coll Surg, 2011 Sep; 213(3):S41-S42.
  1. Singla A, Fleming D, Markley J. Atypical Appearance of Cardiac Papillary Fibroelastoma. In Press, Jan 2012.
  1. Hardaway JC, Bhamidipati CM, Markley, JG (SIC), Gopaldas RR. The Impact of Glycoprotein IIb/IIA Antiplatelet Infusion on the Choice of Revascularization Conduits in Patients Undergoing Coronary Artery Bypass Grafting. J Surg Res. 2012 Jan; 172(2):188.
  1. Bhamidipati CM, Gopaldas RR, Markley JG, Lutz CJ. Is Aortic Valve replacement in Elderly patient’s Justified? J Surg Res.  2012 Jan; 171(2): 187.
  1. Gopaldas RR, Dao TK, Caron NR, Markley JG. Predictors of in-hospital complications after pericardiectomy: A nationwide outcomes study. J Thorac Cardiovasc Surg.  2013 May; 145(5): 1227-33.
  1. Phadke G, Whaley-Connell A, Dalal P, Markley J, Rich A. Acute Cardiac Tamponade: An Unusual Cause of Acute Renal Failure. Cardiorenal Med. 2012 May; 2(2):83-86.
  1. Janzen M, Nichols K, Markley J, Vogel, T, Faizer R. Use of Angio-Seal™ After Iatrogenic Trauma. Missouri Medicine, 2012 Aug; 109(3): 218-8.
  1. Gopaldas RR, Bhamidipati CM, Dao TK, Markley JG. Impact of Surgeon Demographics and Technique on Outcomes After Esophageal Resections: A Nationwide Study. Ann Thorac Surg. 2013 Mar; 95(3): 1064-9.
  1. Gopaldas RR, Overbey DM, Dao TK, Markley JG. The Impact of Academic Calendar Cycle on Coronary Artery Bypass Outcomes: A comparison of Teaching and Non-teaching Hospitals. J Cardiothoracic Surg. 2013 Sep 24; 8: 191.

Abstracts, Posters and Presentations

  1. Markley JG and Nicolosi AC.: Geometry and Function of the Interventricular Septum During Left Heart Bypass in Swine. Fifty Seventh Annual Society of University Surgeons Meeting, Residents’ Session, Washington, DC, February 10, 1996. Presenter: JG Markley.
  2. Markley JG and Nicolosi AC.: Geometry and Function of the Interventricular Septum During Left Heart Bypass in Swine. Milwaukee Academy of Surgery, Resident’s Night, Milwaukee, WI, March 24, 1996. Presenter: JG Markley.
  3. Markley JG and Nicolosi AC.: Geometry and Function of the Interventricular Septum During Left Heart Bypass in Swine. Sixteenth Annual Trauma Clinic Day, Medical College of Wisconsin, Milwaukee, WI, April 16, 1996. Presenter: JG Markley.
  4. Nicolosi AC and Markley JG.: Rapid resolution of systolic and diastolic dysfunction in regionally stunned myocardium by assisted reperfusion.      Circulation 96 (Supp I): I‑372, 1997.
  5. Nicolosi AC, Markley JG, et. al.: Rapid resolution of regional myocardial stunning by assisted reperfusion. 70th American Heart Association Scientific           Sessions, Orlando, FL, Nov 9-12, 1997. Presenter: AC Nicolosi.
  6. Nicolosi AC, Markley JG, West G, Olinger GN. Attenuation of regional myocardial stunning by antagonism of stretch‑activated ion channels. 37th Annual Meeting, Society of Thoracic Surgeons. New Orleans, LA, January, 2001.Presenter: AC Nicolosi.
  7. Markley JG, Wells WJ, Horn MV, Starnes VA, Woo MS.: Bronchial anastomosis complications: Comparison between pediatric living donor double lobar lung transplant and cadaveric double lung recipients. International Society of Heart and Lung Transplantation 22nd Annual Meeting and Scientific Sessions, Washington, DC, April 10‑13, 2000. Presenter: JG Markley.
  8. Markley JG: HIT, HITT, Heparin Alternatives, Cardiopulmonary Bypass. International Medical Lecture Series, 2nd Medical Brigade, Baghdad, Iraq, May 2004.
  9. Markley, JG: Baghdad and Back: Perspective of a Military Surgeon.  General Surgery Grand Rounds, University of Missouri, October 2005.
  10. Khaja A, Gosavi S, Graham V, Loy  T, Markley J, MD, Fay W: Aortic Valve Non-Bacterial Endocarditis in a Patient with  Antiphospholipid Syndrome. Missouri Chapter of the American College of Physicians meeting, September 29, 2006.
  11. Markley, JG: Baghdad and Back: Perspective of a Military Surgeon. Anesthesiology Grand Rounds, University of Missouri, July 2008.
  12. Markley, JG: Patterns of Injury in Modern Warfare. Surgery Fall Symposium, Hugh E. Stevenson, Jr., MD Department of Surgery, University of Missouri School of Medicine, October 2008.
  13. Markley, JG: JTTS Clinical Practice Guidelines for Damage Control Resuscitation at Level IIb and III. Task Force 47th CSH CME lecture series,47th Combat Support Hospital, Mosul, Iraq, October 4, 2009.
  14. Markley, JG: JTTS Guidelines for Vascular Injury. Task Force 47th CSH CME lecture series,47th Combat Support Hospital, Mosul, Iraq, October 20, 2009.
  15. Markley, JG: Injury Patterns in a Modern Theater of Battle. Task Force 47th CSH CME lecture series,47th Combat Support Hospital, Mosul, Iraq, October 20, 2009.
  16. Markley, JG: JTTS Practice Guidelines Management of Patients with Severe Head Trauma. Task Force 47th CSH CME lecture series,47th Combat Support Hospital, Mosul, Iraq, November 3, 2009.
  17. Markley, JG: Management of Airway Injury. Task Force 47th CSH CME lecture series,47th Combat Support Hospital, Mosul, Iraq, December 22, 2009.
  18. Bhamidipati CM, Gopaldas RR, Markley JG, Lutz CJ.  Is Aortic Valve Replacement in Elderly Patients Justified?  J Surg Res 2012, 172(2), 187
  19. Hardaway JC, Bhamidipati CM, Markley JG, Gopaldas RR.  The Impact of Glycoprotein IIB/IIIA Antiplatelet Infusion on the Choice of Revascularization Conduits in Patients Undergoing Coronary Artery Bypass GraftingJ Surg Res 2012, 172(2), 188
  20. Markley, JG: Descending Thoracic Aorta: Aneurysms, Dissections and Transections in the age of TEVAR. Advances in Surgery for Cardiovascular Disease Symposium, University of Missouri Heart and Vascular Center, Columbia, MO August 29, 2015.
  21. Markley, JG: Heart Valve Diseases. Invited Lecturer, Steven’s College, School of Physicians Assistants, Columbia, MO January 3, 2017 
  22. Markley, JG: Heart Valve Diseases. Invited Lecturer, Steven’s College, School of Physicians Assistants, Columbia, MO January 10, 2018 
  23. Markley, JG: Coronary Artery Disease. Invited Lecturer, Steven’s College, School of Physicians Assistants, Columbia, MO January 24, 2018 

 

 

Additional Educational Information

  1. West Torrance HS, Class of 1981
  2. El Camino College 1980-1981 (Calculus and Music performance) 
  3. UCLA (B.S. in Physics and Biology, 1981-1986)
  4. Medical College of Wisconsin (M.D., 1988-1992)
  5. Medical College of Wisconsin General Surgery Residency (1992-1999)
  6. LAC+USC Cardiothoracic Surgery Resident (1999-2002)
  7. Military: Entered Active Duty Army July 2002, ETS July 2012
  8. MIlitary: Officer Basic Course July-Sept 2002
  9. Constructive Credit for Captains Career Course 2005 (after 1st deployment ot Iraq)

Practice Areas

  • Cardiac
  • Thoracic
  • Aorta
  • Aortic valve disease
  • Coronary disease
  • Endocarditis
  • Endovascular
  • Extracorporeal circulation
  • Great vessels
  • Heart failure
  • Critical Care
  • Lung
  • Cancer
  • VATS
  • Mechanical circulatory assistance
  • Mediastinum
  • Minimally Invasive
  • Mitral valve disease
  • Pericardium
  • Basic science
  • Pleura
  • Thoracic
  • Trachea and bronchi
  • Tricuspid valve disease
  • Valve disease
  • Vascular