Pennsylvania State University (1985 BS Biology)
George Washington University (1993 PhD Genetics)
Postdoc, Glaxo-Wellcome Pharmaceuticals (1993-1996)
Assistant Professor, University of Virginia (1996-2003)
Associate Professor, University of Virginia (2003-2013)
Professor of Surgery, University of Virginia (2013 - Present)
Lung Ischemia Reperfusion Injury
Acute Lung Injury
Primary Graft Dysfunction
Molecular & Cell Biology
Compensatory Lung Growth
Dr. Laubach's laboratory conducts translational studies into mechanisms and prevention of lung ischemia-reperfusion (IR) injury following transplantation. IR injury remains a significant and perplexing cause of morbidity and mortality after transplant and also leads to an increased risk for chronic graft dysfunction and rejection. This involves studying cells of the innate immune system (e.g. T cells, macrophages and neutrophils) and the role of cytokines, reactive oxygen species (ROS), adenosine receptor signaling, RAGE signaling, and alveolar epithelial cells. His research utilizes both in vivo and in vitro models to explore inflammatory signaling pathways in cells of the innate immune system as well as epithelial and endothelial cells and the cross-talk between these cells.
Dr. Laubach is an experienced PI with a history of funding from NIH, American Lung Association, American Heart Association, and the Roche Organ Research Foundation. His laboratory is well versed in various surgical, cellular, biochemical and molecular techniques. Finally, Dr. Laubach has extensive experience with laboratory training and research mentorship of >50 trainees including surgery residents, postdocs, graduate students, medical students and undergraduate students.