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Predicting Recurrent Mr Following Mv Repair for Severe Ischemic Mr: Insights from the Ctsn Severe Imr Trial

Friday, November 7, 2014

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Source

Source Name: The Journal of Thoracic and Cardiovascular Surgery

Author(s)

rving L. Kron, Judy W. Hung, Jessica R. Overbey, Denis Bouchard, Annetine C. Gelijns, Alan J. Moskowitz, Pierre Voisine, Patrick T. O’Gara, Michael Argenziano, Robert E. Michler, Marc Gillinov, John D. Puskas, James Gammie, Michael J. Mack, Peter K. Smith, Chittoor Sai-Sudhakar, Timothy J. Gardner, Gorav Ailawadi, Xin Zeng, Karen O’Sullivan, Michael K. Parides, Roger Swayze, Vinod Thourani, Eric A. Rose, Louis P. Perrault, Michael A. Acker

The Cardiothoracic Surgical Trials Network recently reported that a third of patients after mitral valve repair for ischemic MR developed at least moderate recurrent MR at 1 year following surgery.  This begs the question as to which patients with ischemic MR would benefit from repair vs. replacement.  The present publication explored the development of a model to discriminate those patients that were more likely to develop recurrent MR following repair.  The model included the following preoperative variables:  age, BMI, sex, race, EROA, basal aneurysm/dyskinesis, NYHA, history of CABG, PCI, or ventricular arrhythmias.  The model demonstrated good discrimination with an area under the ROC curve of 0.82.  

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