ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Transcatheter Aortic Valve Implantation in the UK: Temporal Trends, Predictors of Outcome and 6 Year Follow Up: A Report from the UK TAVI Registry 2007 to 2012

Sunday, February 22, 2015

Submitted by

Author(s)

Ludman PF, Moat N, de Belder MA, Blackman DJ, Duncan A, Banya W, MacCarthy PA, Cunningham D, Wendler O, Marlee D, Hildick-Smith D, Young CP, Kovac J, Uren NG, Spyt T, Trivedi U, Howell J, Gray H; on behalf of the UK TAVI Steering Committee and the National Institute for Cardiovascular Outcomes Research.

This manuscript reports on data from the UK registry from 2007 to 2012 including 3980 TAVI procedures and a 6 year follow up. The authors carry out a good analysis of trends, risk factors for mortality and results. They found little change in the characteristics of patients treated in the UK by TAVI from 2007 to 2012. Pre-procedural atrial fibrillation was strongly associated with later mortality. Patients who could be treated by the femoral route had a lower mortality than those for whom an alternative route was needed. Unadjusted survival for the direct aortic and the transapical approach were similar at 1 to 2 years. Surgical femoral approaches were used in about 11% in 2007 to 2009, but in later years it increased to about 20%. No difference in outcomes was identified according to need for pacing, or the presence of pre-procedural LBBB. The presence of post procedural aortic regurgitation (moderate or severe) was associated with lower long term survival on multivariate analysis at 1 and 2 years. There was a low incidence of procedural stroke, but it had the strongest independent association with early and late mortality. 

Add comment

Log in or register to post comments