Treatment Approaches and Outcomes for Primary Mediastinal Sarcoma: Analysis of 976 Patients [1]
Engelhardt and colleagues reviewed cases of mediastinal sarcoma in the US National Cancer Database from 2004 to 2012. Overall survival at five years was poor, at only 14.8%, and just under half of patients underwent surgical resection. For patients receiving surgery, an R0 resection was associated with better survival (30.1% versus 18.9%), and surgery combined with radiation therapy was associated with the best survival (40.1%).