TNM Staging for Lung Carcinoma

Primary Tumor (T)
TXPrimary tumor cannot be assessed, or tumor proven by the presence of malignant cells in sputum or bronchial washings but not visualized by imaging or bronchoscopy
T0No evidence of primary tumor
TisCarcinoma in situ
T1Tumor 3 cm or less in greatest dimension, surrounded by lung or visceral pleura, without bronchoscopic evidence of invasion more proximal than the lobar bronchus
T2Tumor with any of the following features of size or extent:
· More than 3 cm in greatest dimension
· Involving main bronchus, 2 cm or more distal to the carina
· Invading the visceral pleura
· Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung
T3Tumor of any size that:
· directly invades the chest wall (including superior sulcus tumors), diaphragm, mediastinal pleura, or parietal pericardium
· is located in the main bronchus less than 2 cm distal to the carina but without involvement of the carina
· is associated with atelectasis or obstructive pneumonitis of the entire lung
T4Tumor of any size that:
· invades the mediastinum, heart, great vessels, trachea, esophagus, vertebral body, or carina
· is associated with a malignant pleural effusion

Regional Lymph Nodes (N)
NXRegional lymph nodes cannot be assessed
N0No regional lymph nodes metastasis
N1Metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes, including direct extension
N2Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s)
N3Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene or supraclavicular lymph node(s)

Distant Metastases (M)
MXPresence of distant metastasis cannot be assessed
M0No distant metastasis
M1Distant metastasis

Stage Grouping
OccultTXN0M0
Stage 0TisN0M0
Stage IT1N0M0
T2N0M0
Stage IIT1N1M0
T2N1M0
Stage IIIAT1N2M0
T2N2M0
T3N0M0
T3N1M0
T3N2M0
Stage IIIBAny TN3M0
T4Any NM0
Stage IVAny TAny NM1