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Seong-Yong Park

Seong-Yong Park, M.D., Ph.D.

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine
81 Irwon-ro, Gangnam-gu
Seoul  06531
South Korea
+82-2-3410-1852;
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Role: 
Surgeon - Cardiothoracic

Background

2004-2005 Severance Hospital, Yonsei University College of Medicine, Seoul, Korea - Internship
2005-2009 Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea – Residency in Department of thoracic and cardiovascular surgery
2009-2012 Center for Lung Cancer, National Cancer Center, Korea – Public Health Doctor
2012-2013 Yonsei University College of Medicine, Seoul, Korea - Clinical fellow in Department of thoracic and cardiovascular surgery
2014-2017.2 Ajou University School of Medicine, Suwon, Korea – Assistant Professor in Department of thoracic and cardiovascular surgery
2017.3-2020.8 Yonsei University College of Medicine, Seoul, Korea – Clinical Assistant Professor in Department of thoracic and cardiovascular surgery
2020.9-2022.1. Yonsei University College of Medicine, Seoul, Korea – Associate Professor in Department of thoracic and cardiovascular surgery
2022.2-Present Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea – Associate Professor in Department of thoracic and cardiovascular surgery

Research

PUBLICATIONS (International)

 

  1. Hsieh M, Park SY, Wen Y, Kim DJ, Chiu C, Chao Y. Impact of prior thoracoscopic experience on the learning curve of robotic McKeown esophagectomy: a multidimensional analysis. Surgical Endoscopy https://doi.org/10.1007/s00464-022-09050-y - Co-first author
  2. Kim HE, Yu WS, Lee CY, Lee JG, Kim DJ, Park SY. Risk factors for pulmonary complications after neoadjuvant chemoradiotherapy followed by surgery for non-small cell lung cancer. Thoracic Cancer. https://doi.org/10.1111/1759-7714.14263 – Co-corresponding author
  3. Kim CG, Kim G, Kim KH, Park S, Shin S, Yeo D, Shim HS, Yoon HI, Park SY, Ha SJ, Kim HR. Distinct exhaustion features of T lymphocytes shape the tumor-immune microenvironment with therapeutic implication in patients with non-small-cell lung cancer. J Immunother Cancer 2021;9:e002780. doi:10.1136/jitc-2021-002780 – co-corresponding author
  4. Yang YH, Park SY, Kim HE, Park BJ, Lee CY, Lee JG, Kim DJ, Paik HC. Effects of mediastinal lymph node dissection in colorectal cancer-related pulmonary metastasectomy. Thorac Cancer. 2021 Oct 30. doi: 10.1111/1759-7714.14196. – Corresponding author
  5. Cho J, Park S, Kim G, Han H, Shim HS, Shin S, Bae Y, Park SY, Ha S, Lee I, Kim HR. Dysregulation of TFH-B-TRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer. Nature Communications volume 12, Article number: 6068 (2021) - co-corresponding author
  6. Kim J, Han MC, Chang JS, Hong C, Kim KH, Byun HK, Park RH, Koom WS, Park SY, Kim JS. Development of a margin determination framework for tumor-tracking radiation therapy with intraoperatively implanted fiducial markers. Front Oncol: doi: 10.3389/fonc.2021.753246 – co-corresponding author
  7. Lee J, Bartholmai B, Peikert T, Chun K, Kim H, Kim JS, Park SY. Evaluation of Computer-Aided Nodule Assessment and Risk Yield (CANARY) in Korean patients for prediction of invasiveness of ground-glass opacity nodule. PLoS ONE 16(6): e0253204. https://doi.org/10.1371/journal.pone.0253204 – co-corresponding author
  8. Park BJ, Shim HS, Lee CY, Lee JG, Kim HR, Lee SH, Hong MH, Park SY. Genetic Analysis and Operative Outcomes in Oncogene-Driven Advanced NSCLC Patients Treated with Cytoreductive Surgery as a Component of Local Consolidative Therapy. Cancers 2021, 13(11), 2549 – co-corresponding author
  9. Kim HE, Park SY, Kim HK, Kim DJ, Kim SI. Prognostic effect of perineural invasion in surgically treated esophageal squamous cell carcinoma. Thorac Cancer 2021 Apr 3. doi: 10.1111/1759-7714.13960 – corresponding author
  10. Park SY, Jung I, Heo SJ, Byun GE, Lee EY, Kim DJ. Comparison of QoL Between Substernal and Posterior Mediastinal Routes in Esophagogastrostomy. J Gastrointest Surg. 2021 Mar;25(3):635-640 – First Author
  11. Park SY, Hong MH, Kim HR, Lee CG, Cho JH, Cho BC, Kim DJ. The feasibility and safety of radical esophagectomy in patients receiving neoadjuvant chemoradiotherapy with pembrolizumab for esophageal squamous cell carcinoma. J Thorac Dis. 2020 Nov; 12(11): 6426–6434. – First author
  12. Park SY, Han KN, Hong JI, Kim HJ, Kim DJ, Choi YH. Subxiphoid approach for robotic single-site-assisted thymectomy. Eur J Cardiothorac Surg 2020 Aug 1;58(Suppl_1):i34-i38. – First author
  13. Yang, YH, Park SY, Kim DJ. Chyle Leakage after Esophageal Cancer Surgery. Korean J Thorac Cardiovasc Surg. 2020 Aug 5;53(4):191-199 – corresponding author
  14. Kim K, Park S, Park SY, Kim G, Park SM, Cho JW, Kim DH, Park YM, Koh YW, Kim HR, Ha S, Lee I. Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer. Genome Med. 2020 Feb 28;12(1):22.
  15. Park SY, Stein H, Heo SY. Preclinical, Cadaveric Study of the Application of da Vinci Single Port System in Thoracic Surgery. J Thorac Dis. 2019 Dec;11(12):5586-5591 – First author
  16. Park SY, Kim DJ, Nam CM, Byun GE, Park HJ, Choi JH. Clinical and economic benefits associated with the use of powered and tissue-specific endoscopic staplers among the patients undergoing thoracoscopic lobectomy for lung cancer. J Med Econ. 2019 Dec;22(12):1274-1280 – First author
  17. Park SY, Byun GE, Lee CY, Lee JG, Kim DJ, Paik HC, Chung KY. Clinical implications of uncertain resection in scenarios of metastasis of the highest or most distant mediastinal lymph node station following surgical treatment of non-small-cell lung cancer. Lung Cancer. 2019 Dec;138:1-5 – First author
  18. Lee JS, Park SY, Kim NY, Kim DW, Oh JE, Heo E, Lee JS, Yoo YC. Anti-Tumor Potential of a 5-HT3 Receptor Antagonist as a Novel Autophagy Inducer in Lung Cancer: A Retrospective Clinical Study with In Vitro Confirmation. J Clin Med. 2019 Sep 3;8(9):1380. – co-first author
  19. Ahn B, Pyo KH, Xin C, Jung D, Shim SH, Lee CY, Park SY, Yoon HI, Hong MH, Cho BC, Kim HR. Comprehensive analysis of the characteristics and treatment outcomes of patients with non-small cell lung cancer treated with anti-PD-1 therapy in real-world practice. J Cancer Res Clin Oncol. 2019 Jun;145(6):1613-1623
  20. Choe E, Cha YJ, Kim J, Pyo KH, Hong MH, Park SY, Shum HS, Jung I, Lee CY, Cho BC, Kim HR. Dynamic changes in PD-L1 expression and CD8+ T cell infiltration in non-small cell lung cancer following chemoradiation therapy. Lung Cancer. 2019 Oct;136:30-36.
  21. Suh JW, Park SY, Lee CY, Lee JG, Kim DJ, Paik HC, Chung KY. Feasibility and surgical outcomes of video-assisted thoracoscopic pulmonary resection in patients with advanced-stage lung cancer after neoadjuvant chemoradiotherapy. Thorac Cancer. 2019 May;10(5):1241-1247. – Corresponding author
  22. Yu WS, Jung J, Shin H2, Roh Y, Byun GE, Kim DJ, Haam S, Park SY. Amylase level in cervical drain fluid and anastomotic leakage after cervical oesophagogastrostomy. Eur J Cardiothorac Surg 2019; doi:10.1093/ejcts/ezz008. – Corresponding author
  23. Park SY, Kim HK, Jang DS, Han KN, Kim DJ. Initial experiences with robotic single-site thoracic surgery for mediastinal masses. Ann Thorac Surg. 2018 Oct 5. pii: S0003-4975 – First author
  24. Park SY, Kim DJ, Suh JW, Byun GE. Comparison of the 11th Japanese classification and the AJCC 7th and 8th staging systems in esophageal squamous cell carcinoma patients. J Thorac Dis 2018;10(8):5039-5046. – First author
  25. Park SY, Suh JW, Kim DJ, Byun GE. Risk factors for weight loss one year after esophagectomy and gastric pull-up for esophageal cancer. J Gastrointest Surg. 2018 Jul;22(7):1137-1143 – First author
  26. Park SY, Suh JW, Kim DJ, Park JC, Kim EH, Lee CY, Lee JG, Paik HC, Chung KY. Near-Infrared Lymphatic Mapping of the Recurrent Laryngeal Nerve Nodes in T1 Esophageal Cancer. Ann Thorac Surg. 2018 Jun;105(6):1613-1620. – First author
  27. Park SY, Kim DJ, Son T, Lee YC, Lee CY, Lee JG, Chung KY. Extent of Mediastinal Lymphadenectomy and Survival in Superficial Esophageal Squamous Cell Carcinoma. Journal of Gastrointestinal Surgery. 2017 Oct;21(10):1584-1590. – First author
  28. Park SY, Suh JW, Narm KS, Lee CY, Lee JG, Paik HC, Chung KY, Kim DJ.   Feasibility of four-arm robotic lobectomy as solo surgery in patients with clinical stage I lung cancer. J Thorac Dis. 2017 Jun; 9(6): 1607–1614. – First author
  29. Park SY, Kim DJ, Kang DR, Haam SJ. Learning curve for robotic esophagectomy and dissection of bilateral recurrent laryngeal nerve nodes for esophageal cancer. Disease of the Esophagus. 2017 December; 30(12):1-9 – First author
  30. Koh YW, Lee SJ, Park SY. Differential expression and prognostic significance of GLUT1 according to histologic type of non-small-cell lung cancer and its association with volume-dependent parameters. Lung Cancer, In press – Corresponding author
  31. Park SY, Kim DJ, Do YW, Suh J, Lee S. The oncologic outcome of esophageal squamous cell carcinoma patients following robot-assisted thoracoscopic esophagectomy with total mediastinal lymphadenectomy. Annals of Thoracic Surgery, In press – First author (SCI)
  32. Park SY, Yoon J, Lee SJ, Haam S, Jung J. Prognostic value of preoperative total psoas muscle area on long-term outcome in surgically treated oesophageal cancer patients. Interactive CardioVascular and Thoracic Surgery (2016). – First author (SCIE)
  33. Jung J, Park SY, Haam S. Efficacy of subpleural continuous infusion of local anesthetics after thoracoscopic pulmonary resection for primary lung cancer compared to intravenous patient-controlled analgesia. J Thorac Dis. 2016 July;8(7):1162-9 – Corresponding author (SCIE)
  34. Choi JR, Park SY, Noh OK, Koh YW, Kang DR. Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure. Annals of Occupational and Environmental Medicine 2016
  35. Yoon S, Jung M, Park SY. Evaluation of surgeon’s muscle fatigue during thoracoscopic pulmonary lobectomy using interoperative surface electromyography. J Thorac Dis. 2016 Jun;8(6):1162-9 – Corresponding author (SCIE)
  36. Park SY, Choi JW, Park J-K, Song EH, Park SA, Kim YS, Shin YS, Kim C-H. Tissue-engineered artificial oesophagus patch using three-dimensionally printed polycaprolactone with mesenchymal stem cells: a preliminary report. Interactive CardioVascular and Thoracic Surgery (2016) 1–6. – First author
  37. Park SY, Cho A, Bae MK, Lee CY, Kim DJ, Chung KY. The value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography for predicting the World Health Organization malignant grade of thymic epithelial tumors: focused in volume-dependent parameters. Clinical Nuclear Medicine. 2016– Co-first author (SCI)
  38. Park SY, Lee SJ, Yoon J. The prognostic value of total lesion glycolysis via 18F-fluorodeoxyglucose PET-CT in surgically treated esophageal squamous cell carcinoma. Annals of Nuclear Medicine. In press. – First author (SCIE)
  39. Jung J, Park SY, Park S, Park J. Prognostic value of the neutrophil-to-lymphocyte ratio for overall and disease-free survival in patients with surgically treated esophageal squamous cell carcinoma. Tumour Biol. 2016 Jun;37(6):7149-54 - Corresponding author (SCI)
  40. Park SY, Yoon JK, Park KW, Lee SJ. Prediction of occult lymph node metastasis using volume-based PET parameters in small-sized peripheral non-small cell lung cancer. Cancer imaging. 2015 15:21 – First author (SCIE)
  41. Park SY, Kim DJ, Jung HS, Yun MJ, Lee JW, Park CK. Relationship between the size of metastatic lymph nodes and positron emission tomographic/computer tomographic findings in patients with esophageal squamous cell carcinoma. The World Journal of Surgery. 2015 Dec 39 (12); 2948-54. – First author (SCI)
  42. Park SY, Kang WJ, Cho A, Chae JR, Cho YL, Kim JY, Lee JW, Chung KY. 64Cu-ATSM hypoxia positron emission tomography for detection of conduit ischemia in an experimental rat esophagectomy model. PLOSone. 2015; 10(6): e0131083. – First author (SCIE)
  43. Park SY, Kim DJ, Yu WS, Jung HS. Robot-assisted thoracoscopic esophagectomy with extensive mediastinal lymphadenectomy: experience with 114 consecutive patients with intrathoracic esophageal cancer. Disease of Esophagus. 2015 Feb 26. doi: 10.1111/dote.12335. – First author (SCIE)
  44. Park SY, Cho A, Yu WS, Lee CY, Lee JG, Kim DJ, Chung KY. Prognostic value of total lesion glycolysis by18F-fluorodeoxyglucose positron emission tomography/computed tomography in surgically resected stage IA non-small cell lung cancer. J Nucl Med. 2015 Jan;56(1):45-9. – Co-first author (SCI)
  45. Bae MK, Lee SK, Kim HY, Park SY, Park IK, Kim DJ, Chung KY. Recurrence after thymoma resection according to the extent of the resection. J Cardiothorac Surg. 2014 Mar 19;9:51.
  46. Kim DJ, Park SY, Lee S, Kim HI, Hyung WJ. Feasibility of a robot-assisted thoracoscopic lymphadenectomy along the recurrent laryngeal nerves in radical esophagectomy for esophageal squamous carcinoma. Surg Endosc. 2014 Jun;28(6):1866-73
  47. Park SY, Kim DJ, Kim J, Aldohayan A, Ahmed I, Husain S, Al Rikabi A, Aldawlatly A, Al Obied O, Hajjar W, Al Nassar S. Immune response after systematic lymph node dissection in lung cancer surgery: Changes of Interleukin-6 level in serum, pleural lavage fluid, and lung supernatant in a dog model. World Journal of Surgical Oncology 2013; 11:270 – First author (SCIE)
  48. Park SY, Lee JG, Kim J, Bae MK, Lee CY, Kim DJ, Chung KY. The influence of smoking intensity on the clinicopathologic features and survival of patients with surgically treated non-small cell lung cancer. Lung Cancer 2013 Sep;81(3):480-6 – First author (SCI)
  49. Park SY, Lee JG, Kim J, Byun GE, Bae MK, Lee CY, Kim DJ, Chung KY. Efficacy of platinum-based adjuvant chemotherapy in T2aN0 stage IB non-small cell lung cancer. J Cardiothorac Surg 2013, 8:151 – First author (SCIE)
  50. Park SY, Lee JG, Kim J, Park Y, Lee SK, Bae MK, Lee CY, Kim DJ, Chung KY. Preoperative serum CYFRA 21-1 level as a prognostic factor in surgically treated adenocarcinoma of lung. Lung Cancer. 2013 Feb;79(2):156-60 – First author (SCI)
  51. Park SY, Lee HS, Jang HJ, Lee JY, Joo J, Zo JI. The role of one-year endoscopic follow-up for esophageal remnant and gastric conduit after esophagectomy with gastric reconstruction for esophageal squamous cell carcinoma. Yonsei Med J. 2013 Mar 1;54(2):381-8 – First author (SCIE)
  52. Park SY, Lee HS, Jang HJ, Joo J, Zo JI. Efficacy of intraoperative, single-bolus corticosteroid administration to prevent postoperative acute respiratory failure after esophageal cancer surgery. Interact CardioVasc Thorac Surg. 2012 Oct;15(4):639-43 – First author (SCIE)
  53. Lee HS, Park SY, Jang HJ, Kim MS, Lee JM, Zo JI. Free jejunal graft for esophageal reconstruction using end-to-side vascular anastomosis and extended pharyngo-jejunostomy. Ann Thorac Surg. 2012 Jun;93(6):1850-4 – Co-first author (SCI)
  54. Park SY, Lee HS, Jang HJ, Joo J, Kim MS, Lee JM, Zo JI. Wedge bronchoplastic lobectomy for nonsmall cell lung cancer as an alternative to sleeve lobectomy. J Thorac Cardiovasc Surg 2012 Apr;143(4):825-831. – First author (SCI)
  55. Jang HJ, Lee HS, Park SY, Zo JI. Comparison of the early robot-assisted lobectomy experience to video-assisted thoracic surgery lobectomy for lung cancer A Single-Institution Case Series Matching Study. Innovations 2011 Sep;6(5):305-10
  56. Park SY, Lee HS, Jang HJ, Lee GK, Chung KY, Zo JI. Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer. Ann Thorac Surg 2011 Jun;91(6):1668-73. – First author (SCI)
  57. Haam SJ, Park SY, Paik HC, Lee DY. Sympathetic Nerve Reconstruction for Compensatory Hyperhidrosis after Sympathetic Surgery for Primary Hyperhidrosis. J Korean Med Sci. 2010: 25:597~601 (SCI)
  58. Yang HS, Park SY, Park HK, Park YH. Palliative atrial switch operation in a 22-year-old patient with transposition of the great arteries. Thorac Cardiovasc Surg. 2010 Feb;58(1):45-7. Epub 2010 Jan 13. (SCI)
  59. Lee JG, Lee CY, Park IK, Kim DJ, Park SY, Kim KD, Chung KY. Number of metastatic lymph nodes in resected non-small cell lung cancer predicts patient survival. Ann Thorac Surg 2008:85:311-5. (SCI)
  60. Youn YN, Park HK, Kim DK, Park SY, Yi G, Park YH. Mid-term results of reconstruction of the right ventricular outflow tract using cryopreserved homografts. Yonsei Med J 2007:48: 639~644 (SCI)
  61. Park SY, Joo HC, Youn YN, Park YH, Park HK. Berry syndrome: two cases of successful surgical repair. Circ J 2008:72:492-5. – First author (SCI)

 

Practice Areas

  • Thoracic
  • Minimally Invasive
  • Robotic
  • VATS
  • Lung
  • Esophagus