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Durable Effectiveness and Safety of Hybrid Ablation Versus Catheter Ablation: 2-year Results From the Randomized CEASE-AF Trial

Thursday, August 14, 2025

Submitted by

Vincent Sier

Source

Source Name: European Journal of Cardio-Thoracic Surgery

Source URL: https://academic.oup.com/ejcts/article/67/7/ezaf146/8213596

Author(s)

Nicolas Doll, Timo Weimar, Dariusz A Kosior, Alan Bulava, Ales Mokracek, Gerold Mönnig, Jonathan Sahu, Steven Hunter, Maurits Wijffels, Bart van Putte, Norman Rüb, Petr Nemec, Tomas Ostrizek, Erik Fransen, Piotr Suwalski

This multicenter randomized trial demonstrated that epicardial-endocardial hybrid ablation (HA) maintained superior effectiveness over endocardial catheter ablation (CA) for nonparoxysmal atrial fibrillation at 24 months (66.3 percent vs. 33.3 percent freedom from AF/atrial flutter/atrial tachycardia), with comparable safety rates and significantly fewer reinterventions after HA.