Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex [1]
This randomized trial among 115 centers assigned patients with NYHA class III or IV heart failure, a short QRS duration, and LV dyssynchrony to device implantation with or without CRT. The study was stopped prematurely by the DSMB for futility. CRT was associated with increased deaths (p=0.02) and there was no difference in the primary outcome of death or hospitalization for worsening heart failure.
Source name:
New England Journal of Medicine
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