This study reports results from the first 2 of 3 incidence screening rounds of the NLST in patients who had no evidence of cancer on the initial screening CT/CXR.  Abnormal results were identified in 28% and 17% on the 1st and 2nd screening CTs compared to 6% and 5% in the CXR screens.  Among detected lung cancers, 47.5% were stage IA in the CT group and 23.5% were stage IA in the CXR group.