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Cancer

February 3, 2020
This interesting study compared bronchial epithelial mutation burden, the primary source of new lung cancers, among nonsmokers, former smokers, and current smokers.  Smoking typically adds 1,000 to 10,000 mutations per cell.  Smoking cessation in this study was associated with replenishment of the abnormal epithelium with cells that are typical of no
February 1, 2020
Individuals at high risk for lung cancer were randomized to low dose CT screening (years 0, 1, 3, and 5.5) or observation.  At 10 years the cumulative rate ratio for lung cancer death was 0.76 in the screened population of men (p=0.01) and 0.67 in the screened population of women, demonstrating a strong benefit for screening.  
January 29, 2020
This video demonstrates the first VATS left upper lobectomy using ArtiSential® wristed instruments.
January 16, 2020
Two groups of Clinical Stage IA lung cancer patients were retrospectively investigated. Ninety-nine patients underwent complex segmentectomy, and 94 patients underwent location-adjusted lobectomy. The results of these two different strategies were compared.
January 10, 2020
Declines in US annual lung cancer mortality rates of 5% for men and 4% for women led improvements in overall cancer mortality rates in the latest update from the American Cancer Society. This is likely linked to efforts at decreasing tobacco use, improved screening, and newer systemic therapies.
January 10, 2020
Benign-appearing lung nodules identified on screening CTs are associated with an increased risk of lung cancer diagnosis 4 to 8 and 8 to 11 years after the scan (RRs 1.9 and 1.6, respectively).
January 8, 2020
In this randomized trial including 330 pts with MPE, talc slurry and VATS talc insufflation under local anesthesia had similar failure rates (24% vs 22%) at 90 days.
January 3, 2020
Using the NCDB, the authors evaluated outcomes for patients with T4a esophageal adenocarcinoma. Receipt of surgery, compared to definitive chemoradiotherapy, offered a significant benefit to overall survival (HR 0.26).  
December 30, 2019
The authors present the case of the surgical treatment of a giant right lung mass, which compresses and displaces adjacent pulmonary parenchyma, mediastinum, and diaphragm, achieving total resection.
December 29, 2019
In this analysis of randomized controlled studies, accupuncture and/or accupressure significantly reduced cancer-associated pain compared to sham procedures.  

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