Segmentectomy Versus Wedge Resection for Non-Small Cell Lung Cancer in High-Risk Operable Patients

The ACOSOG Z4032 trial compared sublobar resection alone to sublobar resection with brachytherapy.   This study compared surgical outcomes for wedge resection vs segmental resection, which were surgical options as part of the  trial.  Wedge resection was associated with a closer resection margin (8mm vs 15mm), a lower rate of nodal upstaging (1% vs 9%), fewer nodal stations sampled (1 vs 3), and a higher rate of no nodal sampling/dissection (41% vs 2%).