In this study the authors evaluate the results of intramyocardial injection of human resident cardiac stem cells and blood derived circulatory angiogenic cells in a mouse myocardial infarction model, comparing the effect on ventricular function and myocardial repair of combined and individual administration of the cells. Better post-infarct ventricular function and myocardial repair were observed with combination therapy than when either type of cell was given alone.
Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium
Submitted by: Erica Curcio
Source: Circulation
Source URL: http://www.ncbi.nlm.nih.gov/pubmed/24030393
Keywords:
Author(s): Latham N, Ye B, Jackson R, Lam BK, Kuraitis D, Ruel M, Suuronen EJ, Stewart DJ, Davis DR.
