Genetic variation in interleukin-17 receptor A is functionally associated with chronic rejection after lung transplantation

Submitted by: Erica CurcioGold Contributor

Source: Journal of Heart and Lung Transplantation
Source URL: http://www.jhltonline.org/article/S1053-2498(13)01451-4/abstract

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Author(s): David Ruttens, Els Wauters, Michal Kiciński, Stijn E. Verleden, Elly Vandermeulen, Robin Vos, Dirk E. Van Raemdonck, Tim S. Nawrot, Diether Lambrechts, Geert M. Verleden, Bart M. Vanaudenaerde

The aim of this genetic study conducted on a large lung transplant population is to demonstrate the relationship between some genetic variants of IL-17 and IL-23 and the risk of development of chronic allograft rejection. This association could lead to new ways of prevention and treatment.

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