CT Screening for Lung Cancer: Nonsolid Nodules in Baseline and Annual Repeat Rounds

The ELCAP data set was evaluated for pts identified with non-solid nodules at baseline or during follow-up.  2392  (4.2%) pts had nonsolid nodules at baseline, of which 73 were diagnosed as adenocarcinoma.  A new nodule was identified in an additional 485 (0.7%) pts, of whom 11 were diagnosed with adenocarcinoma.  Nonsolid nodules improved in 66% of pts.  Median time to cancer treatment was 19 mos, and survival was 100% at a median follow-up of 78 mos.  22 of these pts had a solid component develop during f/u and prior to therapy. The group recommends that nonsolid nodules can be safely followed with CT at intervals of 12 months.