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  1. Cardiac

Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis: The CLEAN-TAVI Randomized Clinical Trial

  • August 9, 2016

Submitted by: Ruben OsnabruggeSilver Contributor

Source: Journal of the American Medical Association
Source URL: http://jama.jamanetwork.com/article.aspx?articleid=2542633

Keywords:

Author(s): Stephan Haussig; Norman Mangner; Michael G. Dwyer; Lukas Lehmkuhl; Christian Lücke; Felix Woitek; David M. Holzhey; Friedrich W Mohr; Matthias Gutberlet; Robert Zivadinov; Gerhard Schuler; Axel Linke

In this study the investigators aimed to study whether a cerebral protection device during TAVI reduced the number of cerebral lesions in patients undergoing TAVI.
In total, 100 patients undergoing TAVI between April 2013 and June 2014 were randomized to either the filter or control group. The number of new lesions at 2 days after TAVI, as measured by diffusion-weighted magnetic resonance imaging (DWMRI), was lower in the filger group (4.00 versus 10.00 in the control group, p

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