Survival Outcomes After Multiple vs Single Arterial Grafting Among Patients With Reduced Ejection Fraction

This retrospective cohort study evaluated the impact of preoperative ischemic heart failure with reduced ejection fraction on long-term outcomes following coronary revascularization using either single or multiple arterial grafting techniques. Data from 59,641 patients (mean age 65.8 years; 81 percent male) across 59 cardiac centers (2001–2020) were analyzed, with patients stratified by perioperative left ventricular ejection fraction (EF). Over a median follow-up of five years, multiarterial grafting was associated with a 19 percent reduction in all-cause mortality for those with normal EF (hazard ratio [HR]=0.81, P