Akshay Patel

This PRE-HIIT randomized controlled trial published in the Annals of Surgery evaluated whether a brief, high-intensity interval training (HIIT) program could improve preoperative cardiopulmonary fitness in patients awaiting complex surgery...

This study investigated whether antifibrotic therapy is associated with a reduced incidence of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Using a large retrospective cohort from the Mayo...

This article presents the first comparative analysis of outcomes after tracheobronchoplasty (TBP) for excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM), two distinct but often conflated causes of excessive central...

The NeoCOAST-2 trial, published in Nature Medicine, evaluates the efficacy and safety of neoadjuvant durvalumab-based combination regimens for resectable stage IIA–IIIB non-small cell lung cancer (NSCLC). This phase II, open-label,...

This article reviews lymph node dissection and its relationship to postoperative chylothorax in thoracic surgery. The authors analyze patterns of nodal involvement, technical considerations during mediastinal lymphadenectomy, and factors contributing...

This article reports the first pig-to-human lung xenotransplantation, marking a major milestone in thoracic transplantation research. A six-gene-edited porcine lung was transplanted into a 39-year-old brain-dead human recipient and monitored...

This article reviews current advances and ongoing challenges in tracheal surgery, focusing on long-segment tracheal resection and reconstruction. The authors highlight that while surgical resection with primary anastomosis remains the...