Akshay Patel

JANS Article

Right Basilar Segmental Autologous Lung Transplantation With Carinal Reconstruction for Central Lung SCC

September 24, 2026 | Akshay PatelSilver Contributor

This case report describes a 75-year-old patient with a centrally located squamous cell carcinoma extending from the carina to the right intermediate bronchus and the superior segment of the lower lobe, while sparing the basilar...

JANS Article

Contemporary Chest Drain Practice After Pulmonary Resection

October 1, 2026 | Akshay PatelSilver Contributor

This prospective European Society of Thoracic Surgeons (ESTS) Drainology Collaborative registry study examined chest-drain practice after pulmonary resection in 3,348 patients across 21 international centers, 88 percent of whom underwent...

JANS Article

Right Basilar Segmental Autologous Lung Transplantation With Carinal Reconstruction for Central Lung SCC

September 24, 2026 | Akshay PatelSilver Contributor

This case report describes a 75-year-old patient with a centrally located squamous cell carcinoma extending from the carina to the right intermediate bronchus and the superior segment of the lower...

JANS Article

An STS General Thoracic Surgery Database Analysis of the Association Between LN Dissection and Chylothorax

September 24, 2026 | Akshay PatelSilver Contributor

This Society of Thoracic Surgeons General Thoracic Surgery Database analysis found that postoperative chylothorax risk increases with the extent of lymph-node dissection during pulmonary resection. Although uncommon, chylothorax was associated...

JANS Article

CT Findings Maintains the Predictive Performance of an Existing Radiograph-Based Donor Lung Acceptability Score

September 17, 2026 | Akshay PatelSilver Contributor

This study assessed whether chest computed tomography (CT) findings improve the validated Lung Donor (LUNDON) score for predicting acceptance of brain-dead donor lungs. Among 2,454 donors who underwent CT, emphysema,...

JANS Article

Reshaping Transplantation With AI, Emerging Technologies and Xenotransplantation

September 11, 2025 | Akshay PatelSilver Contributor

This article explores emerging innovations aimed at addressing the critical challenges of organ transplantation, particularly organ scarcity, rejection, and the burden of lifelong immunosuppression. Key advances include artificial intelligence (AI)...

JANS Article

Inflammatory Diseases and Risk of Lung Cancer Among Individuals Who Have Never Smoked

July 16, 2025 | Akshay PatelSilver Contributor

This article presents a large, population-based study using UK primary care data to identify comorbid conditions associated with lung cancer in never-smokers (LCINS). Across two independent data sets (CPRD-GOLD and...

JANS Article

Touching (Proximity) as a Companion Diagnostic Test

June 5, 2025 | Akshay PatelSilver Contributor

This article discusses a promising diagnostic approach aimed at improving patient selection for immune checkpoint inhibitor (ICI) therapies, particularly in non-small cell lung cancer (NSCLC). The current reliance on PD-L1...

JANS Article

Advancing the Needle on the Management of Resectable EGFR-Positive NSCLC: Is Neoadjuvant Osimertinib the Answer?

June 5, 2025 | Akshay PatelSilver Contributor

This article reviews recent efforts to evaluate the use of osimertinib, a third-generation EGFR tyrosine kinase inhibitor (TKI), in the neoadjuvant setting for patients with resectable EGFR-mutant non-small cell lung...

JANS Article

Estimated Worldwide Variation and Trends in Incidence of Lung Cancer by Histological Subtype in 2022 and Over Time: A Population-Based Study

April 17, 2025 | Akshay PatelSilver Contributor

This article presents a comprehensive epidemiological analysis of lung cancer, focusing on subtype-specific patterns worldwide. Using data from GLOBOCAN 2022 and other international cancer registries, the study estimated more than...

JANS Article

Surgical and Bronchoscopic Lung Volume Reduction for Severe Emphysema: A Systematic Review and Network Meta-Analysis

March 20, 2025 | Akshay PatelSilver Contributor

This meta-analysis compares different lung volume reduction techniques for patients with severe emphysema. Analyzing data from 25 randomized controlled trials with 4,283 patients, the study found that lung volume reduction...

JANS Article

Tumour Spread Through Air Spaces Is a Determiner for Treatment of Clinical Stage I Non-Small Cell Lung Cancer: Thoracoscopic Segmentectomy vs Lobectomy

March 13, 2025 | Akshay PatelSilver Contributor

This study investigates the impact of tumor spread through air spaces (STAS) on surgical outcomes for early-stage non-small cell lung cancer (NSCLC). In a retrospective analysis of 785 patients, 19.2...

JANS Article

Transplantation of a Genetically Modified Porcine Heart Into a Live Human

February 27, 2025 | Akshay PatelSilver Contributor

This article presents findings from the second-ever pig-to-human heart xenotransplant. A 58-year-old patient with end-stage heart failure received a 10-gene-edited porcine heart and was maintained on a novel anti-CD40L immunosuppressive...

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