Mark Ferguson

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Letter From the CTSNet Editor-in-Chief: Mark K. Ferguson, MD (December 2020)

December 21, 2020 | Mark FergusonGold Contributor

From the Editor’s DeskMark K. Ferguson, MDEditor-in-Chief, CTSNet.org December 2020 Colleagues, This is the first in a series of regular communications in my role as CTSNet Editor-in-Chief. As background, I’m a thoracic surgeon at the...

JANS Article

Sybil: A Validated Deep Learning Model to Predict Future Lung Cancer Risk From a Single Low-Dose Chest Computed Tomography

April 19, 2023 | Mark FergusonGold Contributor

This study used lung cancer screening trial low dose CT scans to develop a model (Sybil) that predicts the likelihood of development of a lung cancer within the next year....

JANS Article

A Single-Institutional Experience with 36 Children Smaller Than 5 Kilograms Supported with the Berlin Heart Ventricular Assist Device (VAD) over 12 Years: Comparison of Patients with Biventricular versus Functionally Univentricular Circulation

March 28, 2023 | Mark FergusonGold Contributor

In a study meant to review outcomes in patients less than 5 kg supported by the Berlin Heart pulsatile ventricular assist device (VAD), it was found that the device is...

JANS Article

Outcomes of Treatment for Infective Endocarditis Following Transcatheter Pulmonary Valve Replacement

February 28, 2023 | Mark FergusonGold Contributor

Transcatheter pulmonary valve replacement (TPVR) carries an increased risk of infective endocarditis. This study used data from the Pediatric Health Information System for the period 2010–2020. Ninety-eight hospital admissions for...

JANS Article

Ten-Year Outcomes of Off-Pump vs On-Pump Coronary Artery Bypass Grafting in the Department of Veterans Affairs

April 14, 2022 | Mark FergusonGold Contributor

This 10-year follow-up of the ROBY study reports on the primary end points of all-cause death and the composite of death or revascularization among 2203 patients randomized to off-pump or...

JANS Article

Higher Lung Cancer Incidence in Young Women Than Young Men in the United States

May 23, 2018 | Mark FergusonGold Contributor

The age-specific incidence of non-small cell lung cancer has reversed in individuals born since the 1960s, with women now having a higher incidence than men. This trend is not explained...

JANS Article

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer

May 23, 2018 | Mark FergusonGold Contributor

This is among the first and largest summaries of the use of neoadjuvant PD-1 inhibitor (nivolumab) in patients with resectable lung cancer. The safety profile was adequate, 20 of 21...

JANS Article

Lung Nodule Analysis Model May Reduce Screening False Positives

May 23, 2018 | Mark FergusonGold Contributor

Using eight computed tomography radiographic features in an automated algorithm, differentiating between benign and malignant status of indeterminate pulmonary nodules had an area under the curve of 0.939.

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JANS Article

Association of Surgical Left Atrial Appendage Occlusion With Subsequent Stroke and Mortality Among Patients Undergoing Cardiac Surgery

May 22, 2018 | Mark FergusonGold Contributor

This review of over 75,000 patients from a large administrative database found that occlusion of the left atrial appendage during cardiac surgery was associated with a reduced risk of subsequent...

JANS Article

Doing More With Less: Hand-Powered Ultralow-Cost Paper Centrifuge

May 22, 2018 | Mark FergusonGold Contributor

A centrifuge made of paper and string and powered by hand can separate plasma from whole blood in 90 seconds and permit the diagnosis of malaria in 15 minuntes at...

JANS Article

Expert Consensus Document: Mitochondrial Function as a Therapeutic Target in Heart Failure

May 22, 2018 | Mark FergusonGold Contributor

An interesting, informative, and timely consensus statement on mitochondrial dysfunction in heart failure and how to potentially target these abnormalities therapeutically.

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JANS Article

Feasibility of Bioengineered Tracheal and Bronchial Reconstruction Using Stented Aortic Matrices

May 20, 2018 | Mark FergusonGold Contributor

A landmark article summarizing the early clinical experience of using a cryopreserved aortic homograft with a customized internal stent for major airway replacement.

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JANS Article

Implementing a Thoracic Enhanced Recovery Program: Lessons Learned in the First Year

May 19, 2018 | Mark FergusonGold Contributor

Enhanced recovery programs are very popular now, but their benefits have been mostly theoretical. This article describes challenges and outcomes after initiation of such a program, citing decreased costs, lower...

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