Mark Ferguson

JANS Article

Outcomes Following Aortic Valve Replacement in Children With Conotruncal Anomalies

March 7, 2022 | Mark FergusonGold Contributor

The Pediatric Cardiac Care Consortium was queried for patients undergoing repair of conotruncal abnormalities and subsequent AVR 1982 – 2003. Of 106 patients undergoing AVR, the operative mortality was 12%, and was related to infant...

JANS Article

Sybil: A Validated Deep Learning Model to Predict Future Lung Cancer Risk From a Single Low-Dose Chest Computed Tomography

April 19, 2023 | Mark FergusonGold Contributor

This study used lung cancer screening trial low dose CT scans to develop a model (Sybil) that predicts the likelihood of development of a lung cancer within the next year....

JANS Article

A Single-Institutional Experience with 36 Children Smaller Than 5 Kilograms Supported with the Berlin Heart Ventricular Assist Device (VAD) over 12 Years: Comparison of Patients with Biventricular versus Functionally Univentricular Circulation

March 28, 2023 | Mark FergusonGold Contributor

In a study meant to review outcomes in patients less than 5 kg supported by the Berlin Heart pulsatile ventricular assist device (VAD), it was found that the device is...

JANS Article

Outcomes of Treatment for Infective Endocarditis Following Transcatheter Pulmonary Valve Replacement

February 28, 2023 | Mark FergusonGold Contributor

Transcatheter pulmonary valve replacement (TPVR) carries an increased risk of infective endocarditis. This study used data from the Pediatric Health Information System for the period 2010–2020. Ninety-eight hospital admissions for...

JANS Article

Ten-Year Outcomes of Off-Pump vs On-Pump Coronary Artery Bypass Grafting in the Department of Veterans Affairs

April 14, 2022 | Mark FergusonGold Contributor

This 10-year follow-up of the ROBY study reports on the primary end points of all-cause death and the composite of death or revascularization among 2203 patients randomized to off-pump or...

JANS Article

Exercise is Medicine in Oncology: Engaging Clinicians to Help Patients Move Through Cancer

October 17, 2019 | Mark FergusonGold Contributor

A coalition of international organizations dealing with cancer and sports medicine have updated recommendations, stating that exercise may help prevent cancer and can improve survival in patients with cancer. Methods...

JANS Article

Randomized Trial of Medical Versus Surgical Treatment for Refractory Heartburn

October 17, 2019 | Mark FergusonGold Contributor

Patients with proton-pump inhibitor refractory heartburn have a multitude of underlying causes. In this randomized trial of patients with refractory heartburn, only 21% had symptoms related to gastroesophageal reflux disease....

JANS Article

The Gender Gap in ACS: Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome

October 15, 2019 | Mark FergusonGold Contributor

Using gender specific thresholds for abnormalities in cardiac troponin I, the rate of injury among women increased by 42%. This did not translate into improved management of women, who remained...

JANS Article

Association of Optimism With Cardiovascular Events and All-Cause Mortality

October 12, 2019 | Mark FergusonGold Contributor

The association of cardiovascular events and all-cause mortality with optimism was assessed in this meta-analysis. Optimism was associated with a decreased risk of cardiovascular events (ROR 0.65) and a decrease...

JANS Article

Miscategorization of Deaths in the US Food and Drug Administration Adverse Events Database

October 10, 2019 | Mark FergusonGold Contributor

Reporting of postmarket outcomes for the Sapien 3 and Mitraclip devices frequently misclassified patient deaths as device malfunction or other outcomes. Misclassification for Sapien 3 involved 17.5% of patient deaths,...

JANS Article

Long-Term Outcomes of Lung Transplant With Ex Vivo Lung Perfusion

October 9, 2019 | Mark FergusonGold Contributor

Ex vivo lung perfusion was used in 25% of transplanted lungs in the Toronto program since 2008. This resulted in an increase in the number of transplanted patients without any...

JANS Article

Does Atelectasis Cause Fever After Surgery? Putting a Damper on Dogma

September 22, 2019 | Mark FergusonGold Contributor

The authors point out that randomized trials of incentive spirometry have failed to mitigate early postoperative fevers, traditionally attributed to atelectasis. They propose that an immune response triggered by injured...

JANS Article

Single Radiation Blast Slashes Ventricular Tachycardia Episodes

September 22, 2019 | Mark FergusonGold Contributor

Investigators reported, in abstract form, promising results of a single dose of radiotherapy, delivered with electorphysiologic guidance, for managing ventricular tachycardia. Seventy-eight percent of patients had a clinically important reduction...

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