Stuart Head

JANS Article

The EXCEL trial

December 5, 2016 | Stuart Head

In the largest randomized trial on PCI versus CABG in patients with left main disease (n=1905) and with an inclusion criteria of a SYNTAX score >33, PCI with everolimus-eluting stents was non-inferior to CABG for...

JANS Article

PCI versus CABG in diabetic patients with chronic kidney disease

October 12, 2016 | Stuart Head

In the FREEDOM trial, 1900 diabetic patients were randomized between coronary bypass surgery and percutaneous coronary intervention (PCI). Of these, 451 patients had chronic kidney disease (CKD) with a GFR...

JANS Article

Antiplatelet or anticoagulation after mitral valve repair?

April 28, 2016 | Stuart Head

In a large multi-center, propensity-matched study, Paparella et al found that antiplatelet therapy as opposed to oral anticoagulation therapy initiated after mitral valve repair as antithrombotic prophylaxis caused significantly less...

JANS Article

TAVR for intermediate-risk patients: the PARTNER 2 trial

April 3, 2016 | Stuart Head

The PARTNER 2A trial randomized 2032 patients at intermediate operative risk (mean STS score of 6) to undergo either transcatheter or surgical aortic valve replacement. The primary endpoint of all-cause...

JANS Article

Hybrid revascularization comparable to conventional CABG

April 3, 2016 | Stuart Head

In a propensity-matched analysis, Rosenblum and colleagues found that hybrid revascularization as compared with coronary artery bypass grafting with either single or bilateral internal mammary artery grafts was superior in...

JANS Article

Mechanical valves improve survival in middle-aged patients

January 23, 2016 | Stuart Head

In a propensity-matched analysis of the national database of Sweden, Glaser et al found that survival among patients aged 50-69 who underwent aortic valve replacement was significantly better in those...

JANS Article

Causes of Death Following PCI Versus CABG

January 23, 2016 | Stuart Head

In an analysis from the SYNTAX trial that randomized PCI vs CABG in patients with complex coronary disease, Milojevic et al found that patients had significantly higher rates of cardiac...

Video

Conducting Research During Cardiothoracic Surgery Training

October 22, 2015 | Domenico Pagano…

Domenico Pagano moderates a discussion with Suzanne Arnold, Mostafa Mokhles, Stuart Head, and Ruben Osnabrugge on conducting research during cardiothoracic surgery training. The roundtable was recorded at the 2015 EACTS...

JANS Article

Clinical Trial Design Principles and Endpoint Definitions for Transcatheter Mitral Valve Repair and Replacement: Part 1: Clinical Trial Design Principles: A Consensus Document From the Mitral Valve Academic Research Consortium

July 27, 2015 | Stuart Head

Clinical trials evaluating transcatheter mitral valve interventions for severe mitral regurgitation (MR) are complex. The Mitral Valve Academic Research Consortium has provided a 2-part document with recommendations related to diagnosis...

JANS Article

Survival probability loss from percutaneous coronary intervention compared with coronary artery bypass grafting across age groups

March 28, 2015 | Stuart Head

Benedetto and co-authors analyzed propensity-matched groups of patients who underwent CABG or PCI (n= 1097 pairs) for multivessel disease, and found that outcomes were comparable at 1-year follow-up, while CABG...

JANS Article

Early effects of transcatheter aortic valve implantation and aortic valve replacement on myocardial function and aortic valve hemodynamics: insights from cardiovascular magnetic resonance imaging

March 28, 2015 | Stuart Head

In a prospective study using MRI before and within 14 days after AVR and TAVI, Crouch and co-authors demonstrated that postoperative aortic regurgitation that was higher in the TAVI group...

JANS Article

Trends in use of off-pump coronary artery bypass grafting: Results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database

August 18, 2014 | Stuart Head

Bakaeen and colleagues have retrospectively reviewed the use of off-pump surgery among 2137841 primary isolated CABG operations in the Society of Thoracic Surgeons Database. They showed that off-pump procedures peaked...

JANS Article

Open issues in transcatheter aortic valve implantation.

August 18, 2014 | Stuart Head

In a two-part review, Bax and many other authorities on transcatheter aortic valve implantation (TAVI) provide an extensive overview of the open issues related to patient selection, treatment strategy, and...

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