Vincent Q. Sier

JANS Article

Supra-Annular Perceval Bentall: From Concept to Patient

September 17, 2026 | Vincent SierGold Contributor

This technical report describes the SUpra-annular PERceval Bentall (SUPERB), which utilized a Perceval Plus XL sutureless bovine pericardial valve inside a 28 mm Valsalva Dacron graft. Ex vivo testing involved deploying the Perceval XL into...

JANS Article

Effect of Evolocumab on Grafts Post-Coronary Artery Bypass Surgery

October 1, 2026 | Vincent SierGold Contributor

This post hoc analysis of NEWTON-CABG CardioLink-5 assessed the effects on of evolocumab on 1,275 saphenous vein grafts (SVGs), 514 internal mammary artery grafts, and 39 radial artery grafts by...

JANS Article

Validation of Expected Objective Performance Indicators in Surgical Data Analysis

October 1, 2026 | Vincent SierGold Contributor

This retrospective validation study compared conventional hard boundary objective performance indicators (OPIs) with probabilistic expected OPIs that model uncertainty in surgical step timing. Using 1,016 da Vinci Xi robotic cases...

JANS Article

Comparison of RA and Saphenous Vein as the Third Conduit With BIMA in Coronary Bypass Surgery

September 24, 2026 | Vincent SierGold Contributor

In this 27-year single-center retrospective study, the authors compared radial artery (RA) vs saphenous vein graft (SVG) as the third conduit in patients receiving bilateral internal mammary arteries (BIMA) for...

JANS Article

Supra-Annular Perceval Bentall: From Concept to Patient

September 17, 2026 | Vincent SierGold Contributor

This technical report describes the SUpra-annular PERceval Bentall (SUPERB), which utilized a Perceval Plus XL sutureless bovine pericardial valve inside a 28 mm Valsalva Dacron graft. Ex vivo testing involved...

JANS Article

Six-Year Outcomes After Transcatheter vs Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis

February 26, 2026 | Vincent SierGold Contributor

In this article, the authors report six-year outcomes from the Evolut Low Risk trial, which randomized 1,414 low-risk patients with severe aortic stenosis to transcatheter aortic valve replacement (TAVR) (n=730)...

JANS Article

Postdilation of Evolut Transcatheter Heart Valves: Insights From Bench Testing

February 26, 2026 | Vincent SierGold Contributor

In this brief report, the authors present an ex vivo bench study evaluating the impact of post-dilation strategies on Evolut FX+ transcatheter heart valves (23, 26, 29, and 34 mm)....

Video

First Repairs of the Heart

February 25, 2026 | Vincent SierGold Contributor

In the early 1800s, during the end of the pre-anesthetic era, surgery was defined by speed rather than precision, rendering deliberate intervention on the heart unthinkable. Even after the introduction...

JANS Article

Assessment of Adverse Effects Attributed to Statin Therapy in Product Labels: A Meta-Analysis of Double-Blind Randomised Controlled Trials

February 19, 2026 | Vincent SierGold Contributor

This individual participant data meta-analysis included 23 large double-blind randomized trials with a total of 154,664 participants. The authors systematically evaluated 66 adverse effects listed in statin product labels. In...

JANS Article

Balloon- Versus Self-Expanding Transcatheter Valves for Failed Small Surgical Aortic Bioprostheses: 3-Year Results of the LYTEN Trial

February 19, 2026 | Vincent SierGold Contributor

In this article, the authors present the three-year results of the randomized LYTEN trial comparing balloon-expandable valves (BEV; SAPIEN 3/ULTRA) and self-expanding valves (SEV; Evolut R/PRO/PRO+) for valve-in-valve transcatheter aortic...

JANS Article

Transcatheter Aortic Valve-in-Mechanical Valve Replacement: A First-in-Human Study 

February 19, 2026 | Vincent SierGold Contributor

In this article, the authors present a bench-to-animal-to-human proof of concept for valve-in-mechanical (ViMech) transcatheter aortic valve implantation (TAVI) in patients with failed bileaflet mechanical aortic valves. Bench testing showed...

JANS Article

Sample Size Considerations to Assess Sex-Related Treatment Effects

February 12, 2026 | Vincent SierGold Contributor

This state-of-the-art review examines how trial design and sample size affect the assessment of sex-related treatment effects. Traditional unstructured recruitment often underrepresents women and limits the evaluation of sex-by-treatment interactions....

JANS Article

Endoscopic or Open Radial Artery Harvest in Coronary Artery Bypass Surgery

February 12, 2026 | Vincent SierGold Contributor

In this randomized trial of 300 patients undergoing coronary artery bypass surgery, endoscopic radial artery harvest was compared with open harvest. At three months, mean Hand Function Questionnaire scores were...

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