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LUNG CANCER
A Handbook for Staging, Imaging, and Lymph Node Classification
by Clifton F. Mountain, MD; Herman I. Libshitz, MD; and Kay E. Hermes
Contents | About the Author(s) | Dedication and Acknowledgment
 Preface
page 3 
For the past decade, the scientific community has been well served by wide application of The International System for Staging Lung Cancer1. The system was adopted in 1986 and published in manuals for staging of the American Joint Committee on Cancer (AJCC) and the Union Internationle Contre le Cancer (UICC)2-3. These recommendations for classifying lung cancer according to TNM principles (T-primary tumor, N-regional lymph nodes, M-distant metastasis) and stage grouping of the TNM subsets were based on studies of the survival experience of patients treated for primary lung cancer in a contemporary time frame. With extensive use of the system over time, a need for greater specificity in identifying patient groups became apparent, and two classification problems emerged: (1) heterogeneity existed with respect to the end results for the TNM subsets in stage I and stage IIIA disease, and (2) inconsistency resulted from the use of multiple systems for classifying regional lymph nodes. These problems were addressed and resolved with the least possible disruption in the International Staging System by revising the rules for stage grouping of the TNM subsets and recommending a new schema for classifying regional lymph nodes4-5. The revised rules for stage grouping and the new lymph node mapping schema were adopted by the AJCC and the UICC6-7.

The purpose of this handbook is to provide a convenient reference for using the revised recommendations for staging and regional lymph node classification. Definitions for the TNM descriptors remain the same, as defined in the International System1, except for two minor additions to aid in classifying multiple lung nodules: T4 is used to designate satellite tumor nodules in the ipsilateral primary tumor lobe of the lung; all other separate nodules in the non-primary tumor lobes are designated M1. The revised stage grouping is as follows: T1 N0 M0 tumors are assigned to stage IA and T2 N0 M0 tumors to stage IB; the T1 N1 M0 subset is designated stage IIA and the two subsets, T2 N1 M0 and T3 N0 M0, are assigned to stage IIB; T3 N1 M0 tumors and those classified T1-2-3 N2 M0 are included in stage IIIA; stages IIIB, and IV remain the same.
Copyright © 1999 - 2003 by CF Mountain and HI Libshitz, Houston, Texas. All rights reserved.

Printed in the United States of America by Charles P. Young Company. No part of this manual may be reproduced by any means without the prior written consent of the authors.