Esophagus - Cancer

JANS Article

Long-Term Efficacy of Neoadjuvant Chemoradiotherapy Plus Surgery for the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma

August 12, 2021 | Mark FergusonBronze Contributor

Although the standard of care in the West for regionally advanced esophageal cancer entails induction therapy, this is routinely not the case in China. This randomized trial involving over 450 randomized participants to induction therapy...

JANS Article

Thoracic Surgical Oncology Group: An American Association for Thoracic Surgery Clinical Trials Initiative

June 13, 2024 | Mujtaba MubashirGold Contributor

This editorial summarizes the landscape that led to the founding of the Thoracic Surgical Oncology Group in 2017, in an era when, due to various oncology group reorganizations, a need...

JANS Article

Recovery of Patient-Reported Quality of Life After Esophagectomy

April 13, 2023 | Cameron LindSilver Contributor

This study aimed to measure the quality of life (QOL) as reported by patients after esophagectomy, a procedure which has a high rate of mortality. Researchers found that the one...

JANS Article

Long-Term Quality of Life After Esophagectomy for Esophageal Cancer

February 9, 2023 | Cameron LindSilver Contributor

To understand the shift toward nonsurgical management of esophageal cancer, researchers set out to determine the long-term quality of life (QOL) after esophagectomy. This study found that, in esophagectomy patients...

JANS Article

Global Thoracic Surgery

August 27, 2022 | Emily FarkasBronze Contributor

The delivery of thoracic surgical care in less-resourced areas is explored in this landmark series of articles, hoping to engage the thoracic surgeon in global health equity. There is a...

JANS Article

Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988–2012: A Single-institution, High-volume Experience in China

December 23, 2015 | Mark FergusonBronze Contributor

This longitudinal review of single institution experience with GEJ adenocarcinomas identified time-related trends. The proportion of GEJ tumors compared to all esophageal cancers increased from 22% to 36%. GERD increased...

JANS Article

Adjuvant Therapy for Positive Nodes After Induction Therapy and Resection of Esophageal Cancer

November 15, 2015 | Lisa Brown

The goal of this study was to detemine whether adjuvant chemotherapy leads to a survival benefit in patients with positive LNs who have undergone induction chemoradiation therapy followed by esophagectomy....

JANS Article

The Impact of Severe Anastomotic Leak on Long-term Survival and Cancer Recurrence After Surgical Resection for Esophageal Malignancy

November 11, 2015 | Mark FergusonBronze Contributor

A French multicenter database was used to assess the relationship between severe anastomotic leak on outcomes after esophagectomy. Among 2439 pts, 8.5% developed a severe leak. This was associated with...

JANS Article

Does Quality of Care Matter? A Study of Adherence to National Comprehensive Cancer Network Guidelines for Patients with Locally Advanced Esophageal Cancer

October 12, 2015 | Mark FergusonBronze Contributor

This single institution study evaluated compliance with NCCN guidelines in the management of stage II-III esophageal cancer. Overall compliance was 81%, and was related to younger age, white race, and...

JANS Article

The revised American Joint Committee on Cancer staging system (7th edition) improves prognostic stratification after minimally invasive esophagectomy for esophagogastric adenocarcinoma

September 16, 2015 | Mark FergusonBronze Contributor

The 6th and 7th versions of the AJCC staging system were compared for their prognostic accuracy for patients with esophagogastric adenocarcinomas using an institutional database. The 7th edition system was...

JANS Article

Extent of Lymphadenectomy and Prognosis After Esophageal Cancer Surgery

September 8, 2015 | Mark FergusonBronze Contributor

This single institution study involving 606 patients operated 2000-2012 examined the influence of the extent of lymphadenectomy on survival. The number of nodes resected was not related to all-cause mortality,...

JANS Article

Salvage Surgery After Chemoradiotherapy in the Management of Esophageal Cancer: Is It a Viable Therapeutic Option?

July 23, 2015 | Mark FergusonBronze Contributor

This multicenter retrospective study evaluated the efficacy of salvage esophagectomy after definitive chemoradiotherapy compared to planned esophagectomy after induction chemoradiotherapy. Operative mortality was similarly high in both groups (8.4% vs...

JANS Article

Proposed Modification of Nodal Staging as an Alternative to the Seventh Edition of the American Joint Committee on Cancer Tumor-Node-Metastasis Staging System Improves the Prognostic Prediction in the Resected Esophageal Squamous-Cell Carcinoma

July 17, 2015 | Lisa Brown

Retrospective study of 917 patients undergoing esophagectomy for squamous cell carcinoma at a single hospital in China. In the 7th version of the AJCC staging system for esophageal cancer, nodal...

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