Heart Failure - Nonischemic

JANS Article

Five-Year Follow-Up after Transcatheter Repair of Secondary Mitral Regurgitation

June 1, 2023 | Aristotle ProtopapasGold Commentor

This five-year follow-up of a large randomized controlled clinical trial on outcomes after transcatheter edge-to-edge repair of severe mitral regurgitation, as compared with outcomes after maximal doses of guideline-directed medical therapy alone, suggests superiority of...

JANS Article

Five-Year Follow-Up after Transcatheter Repair of Secondary Mitral Regurgitation

June 1, 2023 | Aristotle ProtopapasGold Commentor

This five-year follow-up of a large randomized controlled clinical trial on outcomes after transcatheter edge-to-edge repair of severe mitral regurgitation, as compared with outcomes after maximal doses of guideline-directed medical...

JANS Article

Mapping Human Cardiac Sarcoidosis by Single Nuclear and Spatial Profiling

September 30, 2022 | Aristotle ProtopapasGold Commentor

This editorial describes the evolving pathway of diagnosing a disease that is predicted to augment the indication for orthotopic cardiac transplantation. Cardiac involvement of sarcoidosis accounts for the majority of...

JANS Article

Effects of Atrial Fibrillation on the Human Ventricle

February 24, 2022 | Aristotle ProtopapasGold Commentor

Interesting study of hypertrophied human cardiomyocytes

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JANS Article

The Right Ventricle During Veno-Venous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: Can We Protect the Injured Ventricle?

January 21, 2022 | Aristotle ProtopapasGold Commentor

An editorial with some interest for the cardiothoracic surgeon, in particular the awareness of changes in the right vantricle during ECMO support , mostly drawn from the recent Covid experiences,...

JANS Article

American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation Guidelines on Selected Topics in Mechanical Circulatory Support

January 30, 2020 | Wei-Guo Ma

The American Association for Thoracic Surgery and International Society for Heart and Lung Transplantation provide a consensus guidelines document on ten important aspects in mechanical circulatory support. These include: 1....

JANS Article

Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability

December 4, 2019 | Aristotle ProtopapasGold Commentor

Well-presented Canadian prospective study juxtaposing a combination of Wells scoring and dimers to the imaging gold standard. It was particularly fascinating to read the referenced assertion that: …..the prevalence of...

JANS Article

The Right Ventricle During Selective Lung Ventilation for Thoracic Surgery

October 14, 2019 | Aristotle ProtopapasGold Commentor

A narrative review offering an intensivists’ viewpoint on specific cardiovascular sequela of double-lumen anaesthesia for pulmonary resections (and by extension, implantation of donor lungs) and other cardiothoracic and vascular operations.

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JANS Article

Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report

September 5, 2019 | Aristotle ProtopapasGold Commentor

The January update of an expert panel from the American College of Chest Physicians on the expanding clinical entity of pulmonary hypertension, especially pertinent to the transplant community.

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JANS Article

Reactive Vasodilation Predicts Mortality in Primary Systemic Light Chain (AL) Amyloidosis

August 13, 2019 | Aristotle ProtopapasGold Commentor

The translational value for cardiac transplantation of this prospective multi-centre clinical study of vasodilation in amyloidosis remains to be evaluated.

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JANS Article

A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report

March 26, 2019 | Wei-Guo Ma

The investigators published the final analysis of the MOMENTUM 3 trial comparing the fully magnetically levitated centrifugal continuous-flow HeartMate 3 pump to the mechanical-bearing axial continuous-flow HeartMate II pump. The...

JANS Article

The Society of Thoracic Surgeons Intermacs Database Annual Report: Evolving Indications, Outcomes, and Scientific Partnerships

February 7, 2019 | Wei-Guo Ma

In the February issue of The Annals, The Society of Thoracic Surgeons published the first annual report after the Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) joined the STS...

JANS Article

Increased Rate of Mortality in Patients Receiving Abiomed Impella RP System

February 5, 2019 | Mark FergusonBronze Contributor

In a letter to healthcare providers, the US FDA summarized a recent evaluation of a postapproval study of the Abiomed Impella RP system. In clinical trials, 73% of patients survived...

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