Lung Cancer - Genetics
An open-access detailed editorial from the official periodical of the International Association for the Study of Lung Cancer
...An open-access detailed editorial from the official periodical of the International Association for the Study of Lung Cancer
...A scholarly and sober narrative review on , as the authors state, a ‘ hot topic’ that is already being debated in Multidisciplinary Meetings and Lung Cnacer Boards.
...This interesting study compared bronchial epithelial mutation burden, the primary source of new lung cancers, among nonsmokers, former smokers, and current smokers. Smoking typically adds 1,000 to 10,000 mutations per...
This brief overview of recently presented improvements in lung cancer therapy highlights the substantial benefits of newer chemotherapy and immunotherapy regimens that are transforming the outlooks of many patients with...
This is an excellent summary of progress during the past year in all aspects of lung cancer, from prevention/detection through molecular therapies and future perspectives. Each section is written by...
One fourth of lung cancer patients are never smokers, consisting of 53% of women with lung cancer and 15% of men; the majority of these are adenocarcinomas. Estrogens interact with...
Investigators from Stanford developed a nine-gene expression predictor for survival outcome in early-stage nonsquamous NSCLC. They developed and validated a quantitative real-time polymerase chain reaction assay easily applicable to routinely...
This comprehensive review outlines changes in the WHO classification of lung tumors, chagnes that will affect our clinical practice in the near future.
...This study explores the genetical contribution to lung cancer in non-smoking patients using a state-wide cancer registry for lung cancer (n=5544). This study provides insight into which non-smoking patients are...
Pts with suspected lung cancer underwent sampling of normal-appearingbronchial epithelial cells in the main bronchi, unrelated to the suspected tumor. Gene expression was analyzed and classified. Classification for cancer was...
Targeting specific genetic changes in cancer cells offers patients personalized therapy for their tumors. The number of identified abnormalities is rapidly increasing, and determining whether they represent driver mutations or...
Concerns remain about the definition of a high risk population who can benefit from low-dose computed tomography screening programs. In this paper, the authors present a promising tool to optimize...

