Lung Cancer - Multimodality Therapy
The neoadjuvant chemoimmunotherapy pathway has become the standard of care for patients with resectable, locally advanced non-small cell lung cancer without actionable mutations. Its increasing use has introduced novel technical challenges, as fibrotic changes, inflammatory...
The neoadjuvant chemoimmunotherapy pathway has become the standard of care for patients with resectable, locally advanced non-small cell lung cancer without actionable mutations. Its increasing use has introduced novel technical...
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with James Cox, Professor of Cardiac Surgery at the Feinberg School of Medicine at Northwestern Medicine in Chicago, Illinois, USA,...
In this Memorial Sloan Kettering series, 11 patients with metastatic DLL3-high pulmonary carcinoid received the DLL3/CD3 bispecific T-cell engager tarlatamab. Eight patients (73 percent) achieved an objective response; all had...
This study reviews 44 patients with stage IB (larger than 4 cm) to IIIA non-small cell lung cancer who were treated on sequential platform arms of the NEOSTAR trial. Twenty-two...
This brief overview of recently presented improvements in lung cancer therapy highlights the substantial benefits of newer chemotherapy and immunotherapy regimens that are transforming the outlooks of many patients with...
A detailed and robust meta-analysis asserting lack of strong evidence supporting either modality.
...To evaluate the benefit of multimodality treatment for patients with limited disease small-cell lung cancer, Weckler and colleagues retrospectively reviewed outcomes for 47 patients treated at their institution between 1999...
Dr Burt gives a brief overview of the considerable advances for patients with thoracic malignancies (non–small cell lung cancer in particular).
...The complete pathologic response rate in this study is revealed to be low, lower than expected after stereotactic ablative radiotherapy (SABR) for early stage non-small cell lung cancer: only 60%....
Forty-nine patients with limited metastatic non-small cell lung cancer (three or fewer metastatic sites) who did not progress on initial systemic therapy were randomized to surgery or RT vs standard...
This comprises the eagerly anticipated summary of the second primary endpoint of the PACIFIC trial of Durvalumab vs placebo in patients who completed CT/RT without progression for unresectable stage III...
This provocative editorial outlines concepts that thoracic surgeons should understand in the era of immunotherapy for potentially resectable N2 disease.
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