In an analysis of 1,826 patients randomized to surgical aortic valve replacement in the three Placement of Aortic Transcatheter Valves (PARTNER) trials, patient-prosthesis mismatch was assessed using transthoracic echocardiography and by the normal reference value for each size and model of implanted valve. Compared with transthoracic echocardiography (21.6 percent), reference values underestimated the incidence of severe patient-prosthesis mismatch (2.1 percent), which was associated with worse all-cause mortality and heart failure rehospitalizations at the two year follow-up.
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Patient-Prosthesis Mismatch After Surgical Aortic Valve Replacement: Analysis of the PARTNER Trials
Submitted by: Jo Chikwe
Source: The Annals of Thoracic Surgery
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Author(s): Vinod H. Thourani, Amr E. Abbas, Julien Ternacle, Rebecca T. Hahn, Raj Makkar, Susheel K. Kodali, Isaac George, Samir Kapadia, Lars G. Svensson, Wilson Y. Szeto, Howard C. Herrmann, Gorav Ailawadi, Jonathon Leipsic, Philipp Blanke, John Webb, Wael A. Jaber, Mark Russo, S. Chris Malaisrie, Pradeep Yadav, Marie-Annick Clavel, Omar K. Khalique, Neil J. Weissman, Pamela Douglas, Jeroen Bax, Abdellaziz Dahou, Ke Xu, Vinayak Bapat, Maria C. Alu, Martin B. Leon, Michael J. Mack, Philippe Pibarot
