Christoper Salerno, MD

Investigator, June 1995 to June 1998, Studies of pig-to-primate xenotransplantation. In vitro, ex vivo and in vivo studies of the molecular and physiologic events leading to graft rejection in pig-to-primate xenotransplantation. Funding: private industry grants totaling $450,695; Minnesota Medical Foundation Grant $7500, March

Investigator, June 1995 to June 1998, Detection of Micrometastases in NSCLC by Reverse Transcriptase Polymerase Chain Reaction. Prospective study using molecular biologic techniques to detect micrometastases in NSCLC. Funding Minnesota Medical Foundation Grant $8000, March 1996; American Cancer Society Grant, $345,000, January

Investigator, June 1996 to June 1998, Clinical application of radiofrequency energy. Large animal model of dysrhythmia ablation using epicardially applied radiofrequency

Investigator, June 1996 to June 1998, Pre-clinical evaluation of prosthetic heart valve substitutes. Large animal models for testing mitral and aortic prosthetic valves in a controlled pre-clinical

Investigator, September 2003 to present, Analysis of Peri-Operative Risk Factors in Heart Transplant Recipients. Prospective and retrospective studies of the heart transplant recipients at the University of Washington.

Co-investigator, September 2004 to present, Cell based therapy for the treatment of heart failure. In vivo pre-clinical and clinical studies to evaluate cell based therapy for heart failure. NHLBI grant in review.

Co-investigator and surgeon, March 2003 – July 2008, The Surgical Treatment for Ischemic Heart Failure (STICH Trial) funded by NHLBI. Clinical trial comparing optimum medical treatment of heart failure (LVEF < 35%) to surgical re-vascularization (with or without ventricular reconstruction).

Investigator and surgeon, August 2004 – August 2005. Phase III Study of AngiomaxÒ (bivalirudin) in Patients with Heparin-induced Thrombocytopenia Thrombosis Syndrome Undergoing Cardiac Surgery on Cardiopulmonary

Investigator and surgeon, June 2004 – January 2005. Comparitive study of AngiomaxÒ (bivalirudin) to Heparin with Protamine Reversal in Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass.

Co-investigator and implanting surgeon, January 2004 – October 2005. Observational, Prospective Evaluation of the St. Jude Medical Toronto Bioprosthesis. The goal is to study safety and efficacy of a stentless, porcine pericardial aortic root

Investigator, June 2005 to present. Heartmate II LVAD Study. A prospective, randomized trial evaluating the Heartmate II LVAD to the Heartmate XVE. University of Washington Principle investigator 2005-2006

Investigator, Paracor Trial. St. Vincent’s Heart Center of

Principle Investigator, Ventracor BTT study: Evaluation of the VentrAssist™ Left Ventricular Assist Device as a Bridge to Cardiac Transplantation. St. Vincent’s Heart Center of Indiana, Indianapolis, Indiana, July 2007-present.

Principle Investigator, Ventracor DT study: Evaluation of the VentrAssist™ Left Ventricular Assist Device as destination therapy for advanced heart failure. St. Vincent’s Heart Center of Indiana, Indianapolis, Indiana, July 2007-present.

Principle Investigator, Field Evaluation of the CardioPAT™ System for Postoperative Cardiac Surgery Subjects at High Risk of Bleeding in the United States. Vincent’s Heart Center of Indiana, Indianapolis, Indiana, July 2007-present.

Principle Investigator, A Post-Approval Study to monitor the clinical performance of the AbioCor Total Artificial Heart in severe end-stage heart disease patients Abiocor St. Vincent’s Heart Center of Indiana, Indianapolis, Indiana, July 2007-present.

Principle Investigator, Patient Discharge Using the AB Portable Driver System. A prospective evaluation of the Abiomed AB5000 portable driver in discharged AB5000 patients. St. Vincent Heart Center of Indiana, Indianapolis, Indiana, August 2008-present.

Member Steering Committee, VentAssist Bridge to Transplant and Destination Therapy studies, January 2008-2009.

Principle Investigator, Terumo DuraHeart LVAD Bridge to Transplant Clinical Trial. St. Vincent Heart Center of Indiana, Indianapolis, IN, 2010-present.

Principle Investigator, Heartware Bridge to Transplant Clinical Trial. St. Vincent’s Heart Center of Indiana, Indianapolis, IN 2009-present.

Principle Investigator, Heartware ENDURANCE Trial. St. Vincent’s Hospital Indianapolis, IN 2010- present.

Member Clinical Events Committee, EvaHeart LVAD U.S. Bridge-to-Transplant Trial, June 2009- present.

Member Scientific Advisory Board, Terumo Heart,

Investigator, Medtronic CoreValve pre-clinical trial, St. Vincent’s Heart Center of Indian 2010 to present.

Investigator, ROADMAP Trial, St. Vincent’s Heart Center of Indiana, December 2011-present.

Co- Principle Investigator, REVIVE-IT Trial, St. Vincent’s Heart Center of Indiana, 2013-present.

Member Clinical Event Committee, Sunshine Heart Trial June 2014-present.

Principle Investigator, Jarvik 2000 Destination Therapy Trial, St. Vincent’s Heart Center of Indiana, 2013-present.

Co-Principle Investigator, Heartmate III Clinical Trial, St. Vincent’s Heart Center of Indiana, 2014- present.

Member, Publication and Presentations Committee, MOMENTUM III Clinical Trial, 2015-present.

Chair, Surgical Committee, MOMENTUM III Clinical Trial, 2015-present.

National PI, Heartmate 3, Thoracotomy Trial (SWIFT).

Principal Investigator, OCS-HEART-OHP-II, 2023-present.

Principle Investigator, INNOVATE Trial (BrioVAD), 2024-present.

Principle Investigator, RELIVE Trial, 2025-present