dr. Daniel J.F.M. Thuijs

SYNTAXES study: An investigator-driven, retrospective study to compare long-term survival-data (10-year follow-up) of patients with coronary artery disease (CAD), previously enrolled in the SYNTAX trial, who were randomized to percutaneous coronary intervention (PCI) using a paclitaxel (TAXUS) drug-eluting-stent (DES) or coronary artery bypass grafting (CABG).

DOI: 10.1016/S0140-6736(19)31997-X
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736 [6](19)31997-X/fulltext
https://clinicaltrials.gov/ct2/show/NCT03417050?term=SYNTAXES&rank=1  [7]

EXCEL study: To establish the safety and efficacy of the commercially approved XIENCE Family Stent System (inclusive of XIENCE PRIME, XIENCE V, XIENCE Xpedition and XIENCE PRO [for use outside the United States [OUS] only]) in subjects with unprotected left main coronary artery disease by comparing to coronary artery bypass graft surgery.
https://clinicaltrials.gov/show/NCT01205776 [8]

REQUEST study: The REQUEST study is an international, multicenter, prospective registry that enrolled 1046 patients in seven well-established CABG centers in Europe (n=4) and North America (n=3) between April 2015 and December 2017. This registry was designed to capture information on any changes in the proposed surgical CABG procedure based on transit time flow measurements (TTFM) and high frequency ultrasound (HFUS) parameters. TTFM and/or HFUS was performed on i) the ascending aorta (canulation, crossclamp and proximal anastomoses sites), ii) the in-situ conduits, iii) the epicardium with the coronary targets, and iv) the completed grafts with their proximal and distal anastomoses.
https://clinicaltrials.gov/ct2/show/NCT02385344 [9]