Risk for Valvular Heart Disease After Treatment for Hodgkin Lymphoma [1]
This retrospective case-control study involving 1852 Hodgkin lymphoma 5-year survivors found that radiation to the heart valves tend to increase the risk for clinically significant valvular heart disease. The rate increased 3.1-fold in patients receiving 31-35 Gy and 11.8-fold in those who received > 40 Gy.