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Salvage Surgery After Chemoradiotherapy in the Management of Esophageal Cancer: Is It a Viable Therapeutic Option? [1]

Submitted by mferguson [2] on Thu, 2015-07-23 18:16

This multicenter retrospective study evaluated the efficacy of salvage esophagectomy after definitive chemoradiotherapy compared to planned esophagectomy after induction chemoradiotherapy.  Operative mortality was similarly high in both groups (8.4% vs 9.3%).  Anastomotic leak was higher after salvage esophagectomy (17.2% vs 10.7%).  3-year survival was similar between the groups.  Salvage esophagectomy for persistent disease resulted in lower survival than when performed for recurrent disease.

Source name: 
Journal of Clinical Oncology
Resource link: 
http://jco.ascopubs.org/content/early/2015/07/14/JCO.2014.59.9092?cmpid=jco_pap_… [3]
Taxonomy: 
Esophagus - Cancer [4]
Esophageal Cancer - Multimodality Therapy [5]
Esophageal Cancer - Surgery [6]
Subspecialty(ies): 
Thoracic [7]
Author(s): 
Sheraz Markar, Caroline Gronnier, Alain Duhamel, Arnaud Pasquer, Jérémie Théreaux, Mael Chalret du Rieu, Jérémie H. Lefevre, Kathleen Turner, Guillaume Luc and Christophe Mariette
Taxonomy2018 vocabulary term reference: 
Esophagus [8]
Cancer [9]
Source URL:https://www.ctsnet.org/jans/salvage-surgery-after-chemoradiotherapy-management-esophageal-cancer-it-viable-therapeutic

Links
[1] https://www.ctsnet.org/jans/salvage-surgery-after-chemoradiotherapy-management-esophageal-cancer-it-viable-therapeutic [2] https://www.ctsnet.org/home/mferguson [3] http://jco.ascopubs.org/content/early/2015/07/14/JCO.2014.59.9092?cmpid=jco_pap_20Jul2015 [4] https://www.ctsnet.org/tags/esophagus-cancer [5] https://www.ctsnet.org/taxonomy/esophageal-cancer-multimodality-therapy [6] https://www.ctsnet.org/taxonomy/esophageal-cancer-surgery [7] https://www.ctsnet.org/categories/thoracic [8] https://www.ctsnet.org/taxonomy2018/esophagus [9] https://www.ctsnet.org/taxonomy2018/cancer