Impressive decrease of death (by approximaltely 40% !) in 2 years from a small RCT in elective structural heart surgery for degeneration. The assumption is a benefit by improvement in right ventricular dynamics
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Cardiac - Physiology
October 21, 2021
A large randomised double-blinded trial reporting a considerable benefit ( 0.79 HR with very small p and supporting confidence intervals) of the Boehringer SGLPT-2 inhibitor regardless of presence of formal diagnosis of diabetes.
October 10, 2021
Scholarly endeavour to digest, in a relatively short and dense manuscript, the State-of-the-Art in assessing the function of the Forgotten Chamber. The notion of surgjcal pericardiotomy as a confounder of decision making is most interesting
October 1, 2021
A scholarly narrative on the utility of quantifying the performance of the right ventricle: the RV has been hitherto empirically assessed in many clinical setups.
May 25, 2021
An authoritative, scholarly but very readable review of the evolution of mechanical circulatory support of the left ventricle from the non-surgical standpoint.
November 17, 2020
A latge RCT of the first myosin inhibitor in severe chronic heart failure: somewhat difficult to interpret results, as deaths were slightly higher in the intervention group while there was no 'significant' benefit in cardiovascular deaths.
August 18, 2020
A review that may affect pharma strategy in the immediate future.
May 23, 2020
a readable review that advances the position that
Adolphe Quetelet's formula is now clinically obsolete
May 11, 2020
Interesting hypothesis in a rodent model of myxomatous degeneration.
April 9, 2020
Another refreshing change of pace with an interesting pre-translational contibution to the genetics of atrial dysrhythmias.