Data from 20 observational studies including nearly 3000 pts were reviewed to assess the prevalence of pre-frailty/frailty and clinical outcomes in older cancer patients. Frailty was identified in 42% and pre-frailty in 43% of patients. Combined frailty was associated with increased all cause mortality (5-yr HR 1.57), postoperative mortality, and p
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Esophageal Cancer - Other
November 20, 2014
October 8, 2014
The histologic response to induction therapy is usually a binary function. In the current study, the authors explored methods of refining the histologic response classification to improve prediction of prognosis for patients with esophageal adenocarcinoma. They identified 3 unique groups: major response in the primary tumor with ypN0; either major
August 31, 2014
In this retrospective study based on a database of 5390 patients with early-stage esophageal cancer, T1a and T1b lesions were treated by endoscopic (26.5%) or surgical resection (73.5%). For patients undergoing surgery, the incidence of lymph node metastasis was 5.0% for T1a and 16.6% for T1b lesions.
May 29, 2014
This retrospective review included 322 pts undergoing open esophagectomy 2005-2010. Gastric empyting procedures included Botox (78), pyloroplasty (199), and pyloromyotomy (45). Botox was associated with more postop reflux symptoms and required more prokinetic agents.