In this manuscript the authors describe their findings in a meta-analysis of 12 randomized placebo-controlled clinical trials involving 2,980 patients undergoing isolated CABG. They found that statin therapy, particularly atorvastatin, initiated before CABG, was associated with a 58% reduction in the risk of postoperative AF.
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Coronary disease
April 12, 2015
April 7, 2015
The authors prospectively performed coronary angiograms in their patients undergoing isolated CABG who demonstrated a rising cardiac troponin I profile in the first 12 hours following heart surgery - despite being asymptomatic. Among a total of 1693 patients from 2005-2011, 29 (1.7%) of patients had a rising CTnI.
April 2, 2015
Repair of this congenital defect in 34 pts was associated with no early mortality and substantial improvement in LV function (EF, shortening fraction, LVEDD). No postoperative circulatory support was required.
March 29, 2015
The authors of this article compared CABG and PCI with second generation drug eluting stents (DES-PCI) in patients with multivessel coronary artery disease. They used data from a large observational registry and applied propensity score matching to create groups with similar baseline characteristics.
March 28, 2015
Benedetto and co-authors analyzed propensity-matched groups of patients who underwent CABG or PCI (n= 1097 pairs) for multivessel disease, and found that outcomes were comparable at 1-year follow-up, while CABG did significantly better during follow-up to 5 years and Kaplan-Meier curves continued to diverge even further after 5 years.
March 16, 2015
In this manuscript the authors present a post-hoc study of the SYNTAX trial. They compare outcomes between those patients on optimal medical therapy (OMT) and non-optimal medical therapy following revascularization for complex coronary artery disease (CAD).
March 14, 2015
This is a very provocative British study that examined whether a more liberal (Hgb < 9 g/dL) versus a more restrictive (Hgb < 7.5 g/dL) transfusion threshold after cardiac surgery is associated with higher morbidity and costs.
March 2, 2015
This interesting article mapped myocardial remodeling in swine after induced MI using serial 3D MRI imaging. Principal strain magnitude and angle were measured, and demonstrated progressive decrease in magnitude and angle rotation away from the site of injury, resulting in adverse remodeling and decreased contractility.
February 28, 2015
Comparing 714 on pump and 714 off pump CABG patients, the investigators investigated the incidence of Acute Kidney Injury (AKI) and whether cardiopulmonary bypass time and or duration were independent contributors to AKI. The investigators concluded that there are no differences in the incidence of AKI during CABG surgery employing CPB.
February 25, 2015
This study describes the development and validation of a risk score for post-operative mortality in patients undergoing surgical ventricular reconstruction (SVR). The study included data on 525 patients who underwent SVR at a single institution since 2001. Most patients (93%) had cocomitant CABG and 27% of patients had concomitant mitral surgery.