Risk Factors of Anastomosis Stricture After Esophagectomy and the Impact of Anastomosis Technique

In 737 patients who underwent esophagectomy at an experienced single center, strictures developed in 105 patients, or 14 percent, that required endoscopic dilation within a year. Risk factors for stricture included anastomotic leaks (hazard ratio [HR], 2.5), and anastomotic techniques other than triangular linear stapling with 60 mm staplers, which had a stricture rate of 3.2 percent (manual sewing: HR, 9.6; circular stapling: HR, 66.5; hybrid linear stapling: HR, 5.4). The authors conclude that a large anastomosis area with triangular linear stapling prevents strictures after esophagectomy.