This population-based cohort study examined midterm outcomes of surgical aortic valve replacement with mechanical or bioprosthetic valves in patients less than 50 years old. A total of 991 patients were included. Multivariable Cox regression showed no significant difference in overall survival, with a median follow up period of 6.2 years. However, reoperation-free survival was significantly decreased and risk of reoperation was increased in those who received bioprosthetic valves. Although a difference in overall survival was not apparent in this study, the lower rate of reoperation with mechanical valves might have an impact on long-term survival.
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Revisiting Aortic Valve Prosthesis Choice in Patients Less Than 50 Years Old: AUTHEARTVISIT 10-Year Results
Submitted by: EACTS Staff
Source: European Journal of Cardio-Thoracic Surgery
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Author(s): Traxler D, Krotka P, Reichardt B, Copic D, Veraar C, Mildner M et al

3 Comments
Interesting
To show a difference between bio and mech valves you need 20 years of follow up. If your follow up time is less than the expected lifetime of the biological valve then both valves will look as if they perform similarly. This is a lifetime management issue and six years doesnt constitute a lifetime
I think they have to till us about any difference regarding bleeding and thromboembolic events