Comparison of Four Mortality Scores for Surgical Repair of Type A Aortic Dissection: A Multicenter External Validation

In the last decades, four different scores for the prediction of mortality following surgery for type A acute aortic dissection (TAAD) were proposed. Researchers aimed to validate these scores in a large external multicenter cohort. The study retrospectively analyzed patients who underwent surgery for TAAD between 2000 and 2020. Patients were enrolled from ten centers in two European countries. Outcomes were determined for early (30-day and/or in-hospital) and one-year mortality. Discrimination, calibration, and observed/expected (O/E) ratio were evaluated for the GERAADA, the UK Aortic, Centofanti’s, and IRAD’s score. The GERAADA score showed the best performance in comparison with other scores. However, none of them achieved both a fair discrimination and good calibration for predicting either the early or the one-year mortality.