In this episode of the CTSNet podcast, The Lifeline, host and nurse educator Jill Ley, Clinical Professor at the University of California San Francisco School of Nursing, Founder of the Essentials of Cardiac Surgical Resuscitation, and former Cardiac Surgery Clinical Nurse Specialist at California Pacific Medical Center in San Francisco, California, USA, speaks with Lakhmir Chawla, Assistant Clinical Professor (Voluntary) of Medicine at the University of California San Diego, USA, and Chief Medical Officer of ExThera Medical. Together, they discuss the science behind new therapies for vasoplegia and potential treatment algorithms to rapidly restore vascular tone and hemodynamic stability.
The discussion explores the history of angiotensin II, including how it emerged as a treatment for vasoplegia, the oxygen transport hypothesis, vasopressin dosing, dopamine and renal blood flow, and the benefits of angiotensin II. They also discuss a patient who underwent left ventricular assist device (LVAD) explantation followed by heart transplantation and how they would approach the patient to achieve positive outcomes. Additional topics include angiotensin II protocols, thromboembolic events, and potential studies involving this patient population.
Every month, The Lifeline features intensive care specialists sharing their expert insights into the rapid and effective management of critically ill cardiac surgical patients. Don’t miss next month’s episode!
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