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  1. Thoracic

The Efficacy of Loco-Regional Ropivacaine Analgesia Via Intercostal Catheters After Lung Resection: A Randomized, Double-Blind, Placebo-Controlled, Superiority Study

  • November 21, 2024

Submitted by: Javeria TariqBronze Contributor

Source: European Journal of Cardio-Thoracic Surgery
Source URL: https://academic.oup.com/ejcts/article/66/4/ezae342/7801212

Keywords:

Author(s): Aljaz Hojski, Monica Krämer, Paulius Gecas, Zeljko Djakovic, Nikolay Tsvetkov, Makhmudbek Mallaev, Daniel Bolliger, Andreas Lampart, Didier Lardinois

Current guidelines advocate for surgically placed intercoastal catheters (ICC) for pain optimization following minimally invasive anatomic lung resection. This double-blind, randomized study aimed to determine the efficacy of loco-regional continuous ropivacaine application through ICC as a method of providing analgesia postoperatively. Data was collected between 2021 and 2023, where patients were randomly allocated to receive ropivacaine 0.2 percent (n=14) versus placebo 0.9 percent NaCl(n=18) through an intercostal catheter for 72 hours following VATS resection for confirmed or suspected Stage I cancer (8th UICC). Patients were matched based on preoperative pain scores and other characteristics. Analysis revealed no positive effects of ropivacaine on postoperative pain or morphine requirements. 

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