Bioprosthetic vs Mechanical Aortic Valve Replacement in Patients 40-75 Years

January 30, 2025

Source: Journal of the American College of Cardiology

Source URL: https://www.jacc.org/doi/10.1016/j.jacc.2025.01.013

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Author(s): Michael E. Bowdish, J. Hunter Mehaffey, Shu-Ching Chang, Patrick O’Gara, Michael J. Mack, Andrew Goldstone, Joanna Chikwe, A. Marc Gillinov, Changfu Wu, Greg Fontana, Joseph Bavaria, Chris Malaisrie, Tsuyoshi Kaneko, Ibrahim Sultan, Moritz W. von Ballmoos, Kathrine Harrington, Jeffrey Jacobs, Vinod Thourani, Wilson Szeto, Joseph Sabik, Robert Habib, and Vinay Badhwar

This study evaluated long-term outcomes of bioprosthetic and mechanical aortic valve replacement (AVR) using data from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (STS-ACSD). It focused on patients who underwent primary isolated AVR, excluding those with certain conditions such as endocarditis, emergency/salvage status, or prior cardiac surgeries. The study found that, after adjusting risks, mechanical valves were associated with lower all-cause mortality compared to bioprosthetic valves for patients aged 60 or younger. These findings provide valuable information for decision-making in choosing between bioprosthetic and mechanical valves, particularly in younger patients.