Vincent Q. Sier

JANS Article

Effect of Evolocumab on Grafts Post-Coronary Artery Bypass Surgery

October 1, 2026 | Vincent SierGold Contributor

This post hoc analysis of NEWTON-CABG CardioLink-5 assessed the effects on of evolocumab on 1,275 saphenous vein grafts (SVGs), 514 internal mammary artery grafts, and 39 radial artery grafts by using coronary computed tomography angiography...

JANS Article

Effect of Evolocumab on Grafts Post-Coronary Artery Bypass Surgery

October 1, 2026 | Vincent SierGold Contributor

This post hoc analysis of NEWTON-CABG CardioLink-5 assessed the effects on of evolocumab on 1,275 saphenous vein grafts (SVGs), 514 internal mammary artery grafts, and 39 radial artery grafts by...

JANS Article

Validation of Expected Objective Performance Indicators in Surgical Data Analysis

October 1, 2026 | Vincent SierGold Contributor

This retrospective validation study compared conventional hard boundary objective performance indicators (OPIs) with probabilistic expected OPIs that model uncertainty in surgical step timing. Using 1,016 da Vinci Xi robotic cases...

JANS Article

Comparison of RA and Saphenous Vein as the Third Conduit With BIMA in Coronary Bypass Surgery

September 24, 2026 | Vincent SierGold Contributor

In this 27-year single-center retrospective study, the authors compared radial artery (RA) vs saphenous vein graft (SVG) as the third conduit in patients receiving bilateral internal mammary arteries (BIMA) for...

JANS Article

Supra-Annular Perceval Bentall: From Concept to Patient

September 17, 2026 | Vincent SierGold Contributor

This technical report describes the SUpra-annular PERceval Bentall (SUPERB), which utilized a Perceval Plus XL sutureless bovine pericardial valve inside a 28 mm Valsalva Dacron graft. Ex vivo testing involved...

JANS Article

Total Endovascular Repair of Ascending Aortic Pathology: The ENDOASC Multicentre Global Study

August 6, 2026 | Vincent SierGold Contributor

This international retrospective study evaluated ascending thoracic endovascular aortic repair (TEVAR) for zone 0 ascending aortic pathology in patients generally unsuitable for open repair. Between 2011 and 2024, 58 patients...

JANS Article

Perivascular Adipose on Relaxation of Internal Thoracic Artery With Surgical Implications: Better Antispastic Effect of Pedicle Than Skeletal Grafts

July 29, 2026 | Vincent SierGold Contributor

This ex vivo study examined human internal thoracic artery (ITA) rings from 94 coronary artery bypass grafting (CABG) patients to assess whether perivascular adipose tissue (PVAT), preserved in pedicled but...

JANS Article

10-Year Outcomes of SAPIEN 3 Transcatheter Aortic Valve Replacement or Surgery in Intermediate-Risk Patients

July 16, 2026 | Vincent SierGold Contributor

This propensity-matched analysis compared 10-year outcomes after SAPIEN 3 transcatheter aortic valve replacement (TAVR) in the PARTNER 2 SAPIEN 3 Intermediate-risk Registry with surgery in the PARTNER 2A trial. Among...

JANS Article

Great Debate: Surgical Aortic Valve Replacement Is First Choice for Aortic Stenosis in Patients With a Life Expectancy Beyond 5 Years

July 16, 2026 | Vincent SierGold Contributor

This special “Great Debate” article discusses whether surgical aortic valve replacement (SAVR) should remain the first choice for aortic stenosis in patients with a life expectancy beyond five years. The...

JANS Article

Superficial Parasternal Intercostal Plane Block With Ropivacaine Versus Placebo for Opioid Exposure After Cardiac Surgery (EPOCH CardioLink-10): A Multicentre, Double-Blind, Randomised Trial

July 2, 2026 | Vincent SierGold Contributor

In the EPOCH CardioLink-10 trial, 318 adults undergoing cardiac surgery via median sternotomy were included in a modified intention-to-treat analysis across four Canadian centers. Patients received bilateral superficial parasternal intercostal...

JANS Article

In Vivo Base Editing of PCSK9 With VERVE-102 for Hypercholesterolemia

June 25, 2026 | Vincent SierGold Contributor

In this article, the authors report interim results of Heart 2, a phase 1, open label, single ascending dose study of VERVE 102, a GalNAc lipid nanoparticle delivering mRNA for...

JANS Article

Surgical Care for Rheumatic Heart Disease Patients: Insights From the Netherlands Heart Registration

June 25, 2026 | Vincent SierGold Contributor

In this article, the authors report a nationwide study evaluating surgical mitral valve replacement (MVR) for rheumatic heart disease (RHD) in all 16 Dutch cardiothoracic centers between 2017 and 2023....

JANS Article

Aortic Homografts for Native and Prosthetic Aortic Valve and Root Endocarditis: Results From the EUropean REgistry of Cryopreserved Aortic Homografts EURECAH

June 18, 2026 | Vincent SierGold Contributor

In this article, the authors report early and long-term outcomes of cryopreserved aortic homografts for complex native and prosthetic aortic valve or root infective endocarditis in the EUropean REgistry of...

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