Clinical Epidemiology

JANS Article

Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

August 31, 2023 | Aristotle ProtopapasGold Commentor

This is an open access genomic study of carotid atheroma in Viennese patients with a useful extensive discussion on potential translational value of the signature of calcification, juxtaposed to sonographic diagnostics and in the quest...

JANS Article

Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years

November 29, 2023 | Aristotle ProtopapasGold Commentor

An important free-access report on the PARTNER 3 trial that discusses the TAVI-first policy in patietns with Society of Thoracic Surgeons Predicted Risk of Mortality risk less than 4% (...

JANS Article

Heart Failure with Preserved Ejection Fraction — A Metabolic Disease?

September 21, 2023 | Aristotle ProtopapasGold Commentor

Professor Pinto raises, in this editorial, a number of important points with regards to heart failure. Starting from a succinct definition of classification by ejection fraction, proceeds to analyse the...

JANS Article

Long Term Health Related Quality of Life After Acute Type B Aortic Dissection: A Cross Sectional Survey Study

September 12, 2023 | Aristotle ProtopapasGold Commentor

This free-access report raises a number of research questions in light of a relatively unsatisfactory response of 55 percent that may reflect unrecorded deaths and should be addressed in future...

JANS Article

Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

August 31, 2023 | Aristotle ProtopapasGold Commentor

This is an open access genomic study of carotid atheroma in Viennese patients with a useful extensive discussion on potential translational value of the signature of calcification, juxtaposed to sonographic...

JANS Article

Long-Term Follow-Up of Ground-Glass Nodules After 5 Years of Stability

August 20, 2019 | Aristotle ProtopapasGold Commentor

Interesting follow-up study of 208 pulmonary ground -glass opacities in 160 subjects, with a yield of three adenocardinomas.

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JANS Article

Silent Brain Infarcts Following Cardiac Procedures: A Systematic Review and Meta‐Analysis

May 15, 2019 | Aristotle ProtopapasGold Commentor

An interesting metanalysis, especially: The ad hoc results of off-pump surgery. The mean number of silent brain infarcts per patient was significantly higher in the transcatheter aortic valve implantation group...

JANS Article

Health, United States: Spotlight Racial and Ethnic Disparities in Heart Disease

April 23, 2019 | Wei-Guo Ma

Five highlights in the CDC’s most recent Health, United States report, based on data from 1999 to 2017: Black patients were more than twice as likely as Asians or Pacific...

JANS Article

Prediction of Premature All-Cause Mortality: A Prospective General Population Cohort Study Comparing Machine-Learning and Standard Epidemiological Approaches

April 1, 2019 | Wei-Guo Ma

Researchers from the University of Nottingham studied 502,628 adults aged 40 to 69 years whose health information was logged in the UK Biobank between 2006 and 2010. Using demographic data...

JANS Article

Impact of Cell Therapy on Cardiovascular Outcomes in Patients With Refractory Angina: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials

April 1, 2019 | Aristotle ProtopapasGold Commentor

A robust meta-analysis of randomized controlled trials on stem cell therapies for refractory angina, offering some encouragement.

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JANS Article

Dietary Restrictions and Nutrition in the Prevention and Treatment of Cardiovascular Disease

March 15, 2019 | Aristotle ProtopapasGold Commentor

Very useful open access review, especially the simple figure on page 959.

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JANS Article

Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass

November 15, 2018 | Aristotle ProtopapasGold Commentor

An interesting randomized controlled trial asserting robustly that endoscopic harvesting of saphenous vein is: (1) better for leg dehiscence and (2) at least noninferior for MACE compared to the conventional...

JANS Article

ECMO for Severe Acute Respiratory Distress Syndrome

September 13, 2018 | Aristotle ProtopapasGold Commentor

Exciting debate on the EOLIA trial! https://www.ctsnet.org/jans/extracorporeal-membrane-oxygenation-severe-a…

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