Coronary Disease - Other

JANS Article

Anomalous Aortic Origin of a Coronary Artery

June 20, 2024 | Jo Chikwe

The prevalence of anomalous aortic origin of a coronary artery is 0.4 percent to 0.8 percent. The decision to operate and choice of procedure can be challenging. This invited expert review by a panel of...

JANS Article

A Promising Heart Drug Fails, Challenging a Long-Held Theory of Disease

September 10, 2026 | Vincent SierGold Contributor

Novo Nordisk reported that the ZEUS study, which involved more than 6,300 patients with heart disease or advanced kidney disease, failed to show a benefit for ziltivekimab vs placebo. Ziltivekimab...

JANS Article

Cardiac Shockwave Therapy in Addition to CABG Improves Myocardial Function in Ischemic Heart Failure: The CAST-HF Trial

June 27, 2024 | Mateo Marin-Cuartas

This study evaluated the outcomes after the use of cardiac shockwave therapy (SWT) combined with coronary artery bypass surgery (CABG) in patients with reduced left ventricular ejection fraction (LVEF) due...

JANS Article

Anomalous Aortic Origin of a Coronary Artery

June 20, 2024 | Jo Chikwe

The prevalence of anomalous aortic origin of a coronary artery is 0.4 percent to 0.8 percent. The decision to operate and choice of procedure can be challenging. This invited expert...

JANS Article

Mechanical Circulatory Support in Cardiogenic Shock — Persistence and Progress

May 18, 2024 | Aristotle ProtopapasGold Commentor

This article presents a succinct but comprehensive expert viewpoint on support in cardiogenic shock using the manuscript of the DanGer trial on promising results of Impella in a highly selected...

JANS Article

miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases

March 30, 2020 | Aristotle ProtopapasGold Commentor

Interesting to follow up the translational potential of this rodent-model of carotid intimal re-hyperplasia/stenosis.

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JANS Article

Percutaneous Coronary Angioplasty Versus Coronary Artery Bypass Grafting in Treatment of Unprotected Left Main Stenosis (NOBLE): A Prospective, Randomised, Open-Label, Non-Inferiority Trial

January 10, 2020 | Aristotle ProtopapasGold Commentor

‘CABG was significantly better than PCI (p=0·0066……..”

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JANS Article

Inflammation as a Treatment Target After Acute Myocardial Infarction

November 18, 2019 | Aristotle ProtopapasGold Commentor

An editorial related to a recent randomized controlled trial suggesting a striking benefit of anti-inflammatory secondary prevention after recent myocardial events.

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JANS Article

Complete Revascularization with Multivessel PCI for Myocardial Infarction

October 19, 2019 | Aristotle ProtopapasGold Commentor

Quite interesting to see that the incidence of revascularisation after multivessel PCA (the additional element on the second co-primary outcome) appears to have occured in more than 1% of the...

JANS Article

A More COMPLETE Picture of Revascularization in STEMI

September 1, 2019 | Aristotle ProtopapasGold Commentor

Interesting viewpoint of a cardiologist on low-SYNTAX subjects.

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JANS Article

Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease

June 27, 2019 | Aristotle ProtopapasGold Commentor

An interesting small British-led randomized controlled trial on modern imaging of coronary atheroma.

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JANS Article

Prophylactic Intra-Aortic Balloon Counterpulsation in High Risk Cardiac Surgery: The PINBALL Pilot Multicentre, Registry-Linked, Randomised, Controlled Feasibility Trial

June 13, 2019 | Aristotle ProtopapasGold Commentor

An intresting pilot that was stopped due to underrecruitment. Commendable mortality in high-risk coronary artery bypass grafting.

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JANS Article

In Global News: Prevalence of Spin in RCT Reports, Setting the Standard for Teamwork, and the Continued Public Health Challenge of Asbestos

May 24, 2019 | Claire Vernon

Patient Care and General Interest Despite being the leading cause of death in the US, heart disease was the most-Googled disease in only one state: Maine. A study that sought...

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